Supercharged vaccine could offer strong protection with just one dose
By delivering an HIV vaccine candidate along with two adjuvants, researchers showed they could generate many more HIV-targeting B cells in mice.
Study in India shows several tactics together boost vaccination against deadly diseases
One combination of methods led to a 44 percent increase in child immunizations.
Particles carrying multiple vaccine doses could reduce the need for follow-up shots
MIT engineers designed polymer microparticles that can deliver vaccines at predetermined times after injection.
Biologists identify targets for new pancreatic cancer treatments
Their study yielded hundreds of “cryptic” peptides that are found only on pancreatic tumor cells and could be targeted by vaccines or engineered T cells.
Is this the new playbook for curing rare childhood diseases?
When his son received a devastating diagnosis, Fernando Goldsztein MBA ’03 founded an initiative to help him and others.
A new vaccine approach could help combat future coronavirus pandemics
The nanoparticle-based vaccine shows promise against many variants of SARS-CoV-2, as well as related sarbecoviruses that could jump to humans.
A blueprint for better cancer immunotherapies
By examining antigen architectures, MIT researchers built a therapeutic cancer vaccine that may improve tumor response to immune checkpoint blockade treatments.
A new approach to modeling complex biological systems
MIT engineers’ new model could help researchers glean insights from genomic data and other huge datasets.
A two-dose schedule could make HIV vaccines more effective
MIT researchers find that the first dose primes the immune system, helping it to generate a strong response to the second dose, a week later.
A new way to reprogram immune cells and direct them toward anti-tumor immunity
MIT scientists’ discovery yields a potent immune response, could be used to develop a potential tumor vaccine.
Researchers study differences in attitudes toward Covid-19 vaccines between women and men in Africa
While women and men self-reported similar vaccination rates, unvaccinated women had less intention to get vaccinated than men.
MIT scientists use a new type of nanoparticle to make vaccines more powerful
Study shows metal-organic particles can both deliver vaccines and act as an adjuvant to generate a strong immune response at a lower dose.
Hitchhiking cancer vaccine makes progress in the clinic
MIT spinout Elicio developed a vaccine based on a lymph node-targeting approach first developed at the Koch Institute. Phase 1 solid tumor clinical trial results are promising so far.
Robert Langer receives Dr. Paul Janssen Award
Award honors “scientists who have made a transformational contribution toward the improvement of human health.”
MIT-led team receives funding to pursue new treatments for metabolic disease
Awarded $65.67 million from ARPA-H, the researchers will work to develop ingestible capsules that deliver mRNA and electric stimuli to treat metabolic disorders such as diabetes.