A blueprint for better cancer immunotherapies
By examining antigen architectures, MIT researchers built a therapeutic cancer vaccine that may improve tumor response to immune checkpoint blockade treatments.
A new approach to modeling complex biological systems
MIT engineers’ new model could help researchers glean insights from genomic data and other huge datasets.
A two-dose schedule could make HIV vaccines more effective
MIT researchers find that the first dose primes the immune system, helping it to generate a strong response to the second dose, a week later.
A new way to reprogram immune cells and direct them toward anti-tumor immunity
MIT scientists’ discovery yields a potent immune response, could be used to develop a potential tumor vaccine.
Researchers study differences in attitudes toward Covid-19 vaccines between women and men in Africa
While women and men self-reported similar vaccination rates, unvaccinated women had less intention to get vaccinated than men.
MIT scientists use a new type of nanoparticle to make vaccines more powerful
Study shows metal-organic particles can both deliver vaccines and act as an adjuvant to generate a strong immune response at a lower dose.
Hitchhiking cancer vaccine makes progress in the clinic
MIT spinout Elicio developed a vaccine based on a lymph node-targeting approach first developed at the Koch Institute. Phase 1 solid tumor clinical trial results are promising so far.
Robert Langer receives Dr. Paul Janssen Award
Award honors “scientists who have made a transformational contribution toward the improvement of human health.”
MIT-led team receives funding to pursue new treatments for metabolic disease
Awarded $65.67 million from ARPA-H, the researchers will work to develop ingestible capsules that deliver mRNA and electric stimuli to treat metabolic disorders such as diabetes.
Noubar Afeyan PhD ’87 to deliver MIT’s 2024 Commencement address
The inventor, entrepreneur, and philanthropist has co-founded and developed over 70 life-science and technology startups.
DNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
MIT’s tiny technologies go to Washington
Cancer nanomedicine was on display at the 2023 White House Demo Day.
3 Questions: Darrell Irvine on making HIV vaccines more powerful
Human volunteers will soon begin receiving an HIV vaccine that contains an adjuvant developed in Irvine’s lab, which helps to boost B cell responses to the vaccine.
MIT engineers design more powerful RNA vaccines
The new approach could lead to intranasal vaccines for Covid-19 and other respiratory diseases.
A snapshot of cancer vaccine development
The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.