Robert Langer wins BBVA Foundation Frontiers of Knowledge Award
Institute Professor honored for groundbreaking work in nucleic acid delivery and nanoparticles.
New CRISPR-based map ties every human gene to its function
Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
Convenience-sized RNA editing
MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.
3 Questions: Daniel Anderson on the progress of mRNA vaccines
Following the successful development of vaccines against Covid-19, scientists hope to deploy mRNA-based therapies to combat many other diseases.
Aging Brain Initiative awards fund five new ideas to study, fight neurodegeneration
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.
Advocating for vaccine equity
Postdoc Digbijay Mahat became a cancer researcher to improve health care in Nepal, but the Covid-19 pandemic exposed additional resource disparities.
New computational tool predicts cell fates and genetic perturbations
The technique can help predict a cell’s path over time, such as what type of cell it will become.
Making RNA vaccines easier to swallow
A pill that releases RNA in the stomach could offer a new way to administer vaccines, or to deliver therapies for gastrointestinal disease.
Speeding up directed evolution of molecules in the lab
Using a new robotic platform, researchers can simultaneously track hundreds of microbial populations as they evolve new proteins or other molecules.
Measuring cancer cell state can reveal drug susceptibility
Study results also show that pancreatic tumor cells can be forced into a more susceptible state by changing their environment.
Engineers devise a way to selectively turn on RNA therapies in human cells
A new RNA-based control switch could be used to trigger production of therapeutic proteins to treat cancer or other diseases.
RNA-targeting enzyme expands the CRISPR toolkit
Exploring diversity among bacterial immune systems, McGovern Institute scientists uncovere a programmable system for precisely targeting and modifying RNA.
New programmable gene editing proteins found outside of CRISPR systems
Researchers find RNA-guided enzymes are more diverse and widespread than previously believed.
Scientists harness human protein to deliver molecular medicines to cells
Made of components found in the human body, the programmable system is a step toward safer, targeted delivery of gene editing and other molecular therapeutics.
SMART researchers develop a method for rapid, accurate virus detection
Four times faster than conventional PCR methods, new RADICA approach is highly specific, sensitive, and resistant to inhibitors.