Newly discovered bacterial communication system aids antimicrobial resistance
SMART researchers find the enzyme RlmN, which directly senses chemical and environmental stresses, can be targeted in drug development.
It takes three to tango: transcription factors bind DNA, protein, and RNA
Whitehead Institute researchers find many transcription factors bind RNA, which fine-tunes their regulation of gene expression, suggesting new therapeutic opportunities.
Scientists pinpoint where thousands of individual proteins are made in intact tissue and single cells
A new technology called RIBOmap can give researchers valuable insight into how protein production in animal and human tissue is altered in disease.
MIT researchers to lead a new center for continuous mRNA manufacturing
A pilot-scale system, enabled by an $82 million award from the FDA, aims to accelerate the development and production of mRNA technologies.
Researchers uncover a new CRISPR-like system in animals that can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
A simple paper test could offer early cancer diagnosis
The new diagnostic, which is based on analysis of urine samples, could also be designed to reveal whether a tumor has metastasized.
Vaccine printer could help vaccines reach more people
The printer generates vaccine-filled microneedle patches that can be stored long-term at room temperature and applied to the skin.
Funding to Daniel Anderson’s lab will advance research on new delivery technology for RNA vaccines and therapies
The global health care company Sanofi is providing $25 million to advance RNA research.
New nanoparticles can perform gene editing in the lungs
Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases.
A new control switch could make RNA therapies easier to program
Using this approach, researchers hope to deliver therapeutic RNA molecules selectively to cancer cells or other target cells.
Researchers map brain cell changes in Alzheimer’s disease
Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue.
Paying it forward
When she’s not analyzing data about her favorite biomolecule, senior Sherry Nyeo focuses on improving the undergraduate experience at MIT.
How Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.
New technologies reveal cross-cutting breakdowns in Alzheimer’s disease
“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.
New CRISPR-based tool inserts large DNA sequences at desired sites in cells
Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.