When cells’ tiny differences have far-reaching implications
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.
Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy
The targeted approach eliminated tumors in mice, with minimal side effects.
Immune system-stimulating nanoparticle could lead to more powerful vaccines
The potent new adjuvant could be used to help make vaccines against HIV and other infectious diseases.
Technique recovers lost single-cell RNA-sequencing information
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.
A step toward a universal flu vaccine
With computer models and lab experiments, researchers are working on a strategy for vaccines that could protect against any influenza virus.
Engineers use “DNA origami” to identify vaccine design rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
Researchers identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.
Structure of T cell epitopes a decisive factor in natural HIV control, study finds
Researchers apply network theory to HIV protein structure, uncovering a vital link between connectivity and protective immune response.
Study offers new way to discover HIV vaccine targets
Ragon Institute researchers develop a method to identify weak points in viral proteins that could be exploited for vaccine development.
Bringing a new perspective to infectious disease
Enlisted in the fight against HIV, MIT engineers and scientists contribute new technology, materials and computational studies.
Monitoring how T cells respond to HIV
New technology could help AIDS researchers develop new vaccines.
Scientists reveal HIV weakness
Vaccines that target newly identified viral protein sequences could be more effective than previous efforts.
New insights into the mystery of natural HIV immunity
A new finding from the Ragon Institute of MGH, MIT and Harvard may have implications for designing an effective AIDS vaccine.
3 Questions: AIDS researchers on new vaccine results
Partial success of a new AIDS vaccine offers clues to help develop a stronger vaccine, say MIT’s Arup Chakraborty and MGH’s Bruce Walker.