Study finds a surprising new role for a major immune regulator
In addition to turning on genes involved in cell defense, the STING protein also acts as an ion channel, allowing it to control a wide variety of immune responses.
Vaccine delivers a boost to T cell therapy
The new strategy may enable engineered T cells to eradicate solid tumors such as glioblastoma.
New model offers a way to speed up drug discovery
By applying a language model to protein-drug interactions, researchers can quickly screen large libraries of potential drug compounds.
Seychelle Vos and Hernandez Moura Silva named HHMI Freeman Hrabowski Scholars
The program supports early-career faculty who have strong potential to become leaders in their fields and to advance diversity, equity, and inclusion.
When cells’ tiny differences have far-reaching implications
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.
Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy
The targeted approach eliminated tumors in mice, with minimal side effects.
Immune system-stimulating nanoparticle could lead to more powerful vaccines
The potent new adjuvant could be used to help make vaccines against HIV and other infectious diseases.
Technique recovers lost single-cell RNA-sequencing information
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.
A step toward a universal flu vaccine
With computer models and lab experiments, researchers are working on a strategy for vaccines that could protect against any influenza virus.
Engineers use “DNA origami” to identify vaccine design rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
Researchers identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.
Structure of T cell epitopes a decisive factor in natural HIV control, study finds
Researchers apply network theory to HIV protein structure, uncovering a vital link between connectivity and protective immune response.
Study offers new way to discover HIV vaccine targets
Ragon Institute researchers develop a method to identify weak points in viral proteins that could be exploited for vaccine development.
Bringing a new perspective to infectious disease
Enlisted in the fight against HIV, MIT engineers and scientists contribute new technology, materials and computational studies.
Monitoring how T cells respond to HIV
New technology could help AIDS researchers develop new vaccines.