A new computational framework illuminates the hidden ecology of diseased tissues
The MESA method uses ecological theory to map cellular diversity and spatial patterns in tissues, offering new insights into disease progression.
A new vaccine approach could help combat future coronavirus pandemics
The nanoparticle-based vaccine shows promise against many variants of SARS-CoV-2, as well as related sarbecoviruses that could jump to humans.
A two-dose schedule could make HIV vaccines more effective
MIT researchers find that the first dose primes the immune system, helping it to generate a strong response to the second dose, a week later.
New Ragon Institute building opens in the heart of Kendall Square
The building will serve as a hub for research on the development of immunology-based treatments.
DNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
Researchers improve blood tests’ ability to detect and monitor cancer
The advance makes it easier to detect circulating tumor DNA in blood samples, which could enable earlier cancer diagnosis and help guide treatment.
Twelve with MIT ties elected to the National Academy of Medicine for 2023
Five MIT faculty, along with seven additional affiliates, are honored for outstanding contributions to medical research.
Study finds a surprising new role for a major immune regulator
In addition to turning on genes involved in cell defense, the STING protein also acts as an ion channel, allowing it to control a wide variety of immune responses.
Vaccine delivers a boost to T cell therapy
The new strategy may enable engineered T cells to eradicate solid tumors such as glioblastoma.
New model offers a way to speed up drug discovery
By applying a language model to protein-drug interactions, researchers can quickly screen large libraries of potential drug compounds.
Seychelle Vos and Hernandez Moura Silva named HHMI Freeman Hrabowski Scholars
The program supports early-career faculty who have strong potential to become leaders in their fields and to advance diversity, equity, and inclusion.
When cells’ tiny differences have far-reaching implications
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.
Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy
The targeted approach eliminated tumors in mice, with minimal side effects.
Immune system-stimulating nanoparticle could lead to more powerful vaccines
The potent new adjuvant could be used to help make vaccines against HIV and other infectious diseases.
Technique recovers lost single-cell RNA-sequencing information
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.