Researchers at MIT have developed a mobile printer that could create microneedle patches for mRNA vaccine delivery. “These "microneedle patches" offer a range of advantages over traditional jabs in the arm, including that they can be self-administered, are relatively painless, could be more palatable to the vaccine-hesitant and can be stored at room temperature for long periods of time,” writes Daniel Lawler for Agence France-Presse.
Research scientist Ana Jaklenec spoke with Jonathan Grinstein at Genetic Engineering & Biotechnology News about a new microneedle patch printer she and her colleagues have developed that may one day enable on-demand vaccine manufacturing. “The idea was that you could, in an emergency situation, deploy some of these printers and locally vaccinate the population to prevent the global spread of infection,” says Jaklenec.
In a new study, researchers at MIT showed that they “were able to interfere with an enzyme typically found to be overactive in the brains of Alzheimer’s patients,” reports Alex Mitchell for The New York Post. After using a peptide to treat the overactive enzyme, they found that “the peptide shows protective effects against loss of neurons and also appears to be able to rescue some of the behavior deficits,” says Prof. Li-Huei Tsai.
Callie Gade and Nate Bonham of CNN’s Discovery Daily Podcast spotlight how researchers from MIT developed a 3D printed replica of the human heart that can help doctors customize treatments for patients before conducting open heart surgery or other intrusive procedures. “These more patient-specific heart replicas can help future researchers develop and identify treatments for people with unique health problems,” says Gade.
Dr. Akshay Syal, a medical fellow for NBC News, discusses how MIT researchers have developed a new technique to 3D print custom replicas of the human heart.
Bloomberg reporter Tanaz Meghjani writes that MIT researchers created a new system to 3D print a customized replica of the human heart, which could help improve replacement valve procedures. The new system “mimics blood flow and pressure in individual diseased hearts, suggesting a way to predict the effects of various replacements and select the best fit, avoiding potential leakage and failure,” Meghjani writes.
MIT engineers have developed a new technique for 3D printing a soft, flexible, custom-designed replica of a patient’s heart, report Gabrielle Emanuel and Amy Sokolow for WBUR. The goal of the research is to “provide realistic models so that doctors, researchers and medical device manufacturers can use them in testing therapies for different types of heart disease,” Emanuel and Sokolow explain.
MIT scientists have found that silent synapses - a type of memory-forming synapse - are present in the adult brain, reports The Economist. The discovery of these silent synapses, explains Prof. Mark Harnett, “is a lever for us to get into understanding learning in adults and how potentially we can get access to make it not degrade over the course of aging or disease.”
Researchers at MIT have found “the brain is not wired to transmit a sharp ‘stop’ command in the most direct or intuitive way,” reports Kevin Hartnett for Quanta Magazine. The brain “employs a more complicated signaling system based on principles of calculus,” writes Hartnett.
Researchers at MIT have developed new gene-editing technology that can move large sequences of DNA into the human genome, reports Ryan Cross for The Boston Globe. “The molecular tool gives scientists a new way to completely replace broken genes, paving the way to potential cures for diseases such as cystic fibrosis,” writes Cross.
MIT researchers have found that standard autism diagnostic tests could be “stymieing discovery of sex differences in autism,” reports Ingrid Wickelgren for Scientific American. “To qualify for the study, prospective participants had to take a standard activity-based assessment for autism to confirm their diagnosis,” says Wickelgren. “After testing, half of the 50 girls and women who would otherwise be eligible for the scientists’ study did not meet the test’s criteria for autism.”
Researchers at MIT have found indoor humidity levels can influence the transmission of Covid-19, reports Dennis Thompson for US News & World Report. “We found that even when considering countries with very strong versus very weak Covid-19 mitigation policies, or wildly different outdoor conditions, indoor — rather than outdoor — relative humidity maintains an underlying strong and robust link with Covid-19 outcomes,” explains Prof. Lydia Bourouiba.
MIT researchers have found that relative humidity “may be an important metric in influencing the transmission of Covid-19,” reports Sophie Mellor for Fortune, “Maintaining an indoor relative humidity between 40% and 60% – a Goldilocks climate, not too humid, not too dry – is associated with relatively lower rates of Covid-19 infections and deaths,” writes Mellor.
A stamp-sized reusable ultrasound sticker developed by researchers in Prof. Xuanhe Zhao’s research group has been named one of the best inventions of 2022 by TIME. “Unlike stretchy existing ultrasound wearables, which sometimes produce distorted images, the new device’s stiff transducer array can record high-resolution video of deep internal organs (e.g. heart, lungs) over a two-day period,” writes Alison Van Houten.
Scientists at MIT have found that specific neurons in the human brain light up whenever we see images of food, reports Dr. Mallika Marshall for CBS Boston. “The researchers now want to explore how people’s responses to certain foods might differ depending on their personal preferences, likes and dislikes and past experiences,” Marshall.