Understanding genetic circuits and genome organization
Assistant professors Pulin Li and Seychelle Vos are investigating how cells become tissues and the proteins that organize DNA.
Using CRISPR to program gels with new functions
Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.
High-precision technique stores cellular “memory” in DNA
Engineers program human and bacterial cells to keep a record of complex molecular events.
To divide or not to divide?
Whitehead Institute team reveals molecular program that controls cells’ capacity for division.
An emerging view of RNA transcription and splicing
Whitehead Institute scientists find chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression.
Study furthers radically new view of gene control
Along the genome, proteins form liquid-like droplets that appear to boost the expression of particular genes.
A new way to block unwanted genetic transfer
Researchers identify a strategy to prevent mobile genetic elements from breaching the bacterial cell wall.
Scientists look to synthetic biology and 3-D printing for life support in space
Do-it-yourself bio and maker communities can help NASA meet needs of long-distance missions.
New CRISPR platform expands RNA editing capabilities
The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.
Record-breaking DNA comparisons drive fast forensics
Developed at MIT Lincoln Laboratory, IdPrism and its award-winning algorithms provide rapid analysis for complex forensic DNA samples.
A chemical approach to imaging cells from the inside
Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.
How to detect life on Mars
Scientists from the Search for Extra-Terrestrial Genomes instrument team develop method to detect the tiniest traces of life on other planetary bodies.
New gene-editing system precisely inserts large DNA sequences into cellular DNA
Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.
Drug makes tumors more susceptible to chemo
Compound that knocks out a DNA repair pathway enhances cisplatin treatment and helps prevent drug-resistance.
A “biomultimeter” lets scientists measure RNA and protein production in real-time
Fluorescent tagging system can expedite the process of designing genes and personalizing medicine.