Neuroscientists identify cells especially vulnerable to Alzheimer’s
Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.
A shot in the arm
Researchers develop new, patient-friendly hydrogel platform for administering lifesaving biologics.
3 Questions: Mriganka Sur on the research origins of the first approved drug to treat Rett syndrome
On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1. The MIT professor's original research showing that IGF-1 could treat Rett was published in 2009.
How Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.
Brandon Ogbunu is a radical collaborator
MLK Visiting Professor tries to “maximize connection time” while studying protein evolution.
Molecules found in mucus could prevent cholera infection
Harnessing these protective molecules may offer a new way to treat the disease, which spreads through contaminated water.
Large language models help decipher clinical notes
Researchers used a powerful deep-learning model to extract important data from electronic health records that could assist with personalized medicine.
New CRISPR-based tool inserts large DNA sequences at desired sites in cells
Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.
Nanosensors target enzymes to monitor and study cancer
By analyzing enzyme activity at the organism, tissue, and cellular scales, new sensors could provide new tools to clinicians and cancer researchers.
Celebrating 20 years of discovery, Picower Institute looks ahead to continuing impact
At an exhibition marking two decades since a transformative gift from the Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond.
MIT events illuminate critical need for menstruation science
“AI for endometriosis? If only there were data!”
SMART researchers develop quick test to determine immunity against Covid-19
Test that measures a person’s antibodies requires a drop of blood and takes just 10 minutes to show results.
Neurodegenerative disease can progress in newly identified patterns
A machine-learning method finds patterns of health decline in ALS, informing future clinical trial designs and mechanism discovery. The technique also extends to Alzheimer’s and Parkinson’s.
In-home wireless device tracks disease progression in Parkinson’s patients
By continuously monitoring a patient’s gait speed, the system can assess the condition’s severity between visits to the doctor’s office.
Using machine learning to identify undiagnosable cancers
A new model that maps developmental pathways to tumor cells may unlock the identity of cancers of unknown primary.