“There’s an enormous richness of information by looking in the water that’s indicative of what’s going in a city in a real-time fashion,” says Prof. Eric Alm in an interview with Wudan Yan of The Daily Beast of his idea to examine public health by tracking the transmission of pathogens in sewers.
WBUR’s Deborah Becker and Lynn Jolicoeur report on the new MIT-MGH partnership aimed at developing better tools to treat disease. Prof. Arup Chakraborty hopes the collaboration will allow researchers to take risks. “Safe ideas are often not the transformative ones,” he says.
Brendan Borrell writes for Scientific American about how MIT researchers have engineered the DNA of E.coli to detect and record environmental information. “Building gene circuits requires not only computation and logic, but a way to store that information,” says Prof. Timothy Lu. “DNA provides a very stable form of memory and will allow us to do more complex computing tasks.”
MIT engineers have altered the DNA of E.coli so that it can store memories, reports Colin Barras for New Scientist. The research could “pave the way for cellular biographers that can be inserted into our bodies for the inside scoop on our health,” Barras explains.
Nature highlights the top science news of the week, including the new interdisciplinary center at MIT aimed at examining the microbiome. “The center will initially focus on inflammatory bowel disease, but organizers hope to eventually broaden the scope to diseases such as multiple sclerosis, arthritis and autism,” Nature reports.
In a piece for The Boston Globe, Meredith Goldstein writes that Institute Professor Robert Langer received a Kyoto Prize at a ceremony in Japan for his work with tissue engineering.
Thomas Burton of The Wall Street Journal writes that MIT researchers were among those awarded the first research grants under President Obama’s new BRAIN Initiative. Burton writes that one of the MIT grants will go toward “determining which exact brain circuits are involved in generating short-term memories that influence decisions.”
Boston Globe reporter Deborah Kotz writes that MIT researchers have been awarded new grants from the National Institutes of Health to further brain research. “Biophysicist Alan Jasanoff received a grant to develop imaging agents for functional MRI imaging that would target the flow of calcium into and out of brain cells,” writes Kotz of one of the MIT grants.
MIT neuroscientists were among the recipients of new grants for brain research from the National Institutes of Health, reports Jon Hamilton for NPR. Hamilton explains that as part of one grant, “Researchers from the Massachusetts Institute of Technology will try to adapt functional MRI so that it can show the activity of individual brain cells.”
Loren Grush of Popular Science writes about a new type of antibiotic developed by MIT researchers that could help kill drug-resistant bacteria. “[T]he team developed their own gene-editing system, capable of turning off certain bacterial genes that spur antibiotic resistance,” Grush explains.
A team led by Professor Timothy Lu has developed a new class of antibiotic that can selectively kill bacteria based on their genes, reports Michael Eyre for BBC News. "This is an enabling toolkit for the basic scientists to now start probing these systems a little bit better,” says Lu.
Researchers at MIT have developed a waterproof glue based on the proteins that allow shellfish to cling to rocks, reports Brooks Hays for UPI. "We're trying to figure out if by adding other mussel foot proteins, we can increase the adhesive strength even more and improve the material's robustness," said Professor Timothy Lu.
Francie Diep writes for Popular Science about a new waterproof adhesive developed by Professor Timothy Lu’s team. “The glue, which works underwater, incorporates proteins that mussels normally use to adhere to rocks, jetties, and larger sea critters,” writes Diep.
CBS News reports that MIT engineers have identified several combinations of genes that make bacteria more vulnerable to antibiotics. This research could help in the fight against “superbugs,” drug-resistant bacteria that kill at least 23,000 people per year in the U.S.
Amanda Schaffer of The Atlantic writes about OpenBiome, a non-profit stool bank founded by MIT students Mark Smith and James Burgess. “When OpenBiome was established, my quality of life went through the roof,” says Amy Barto, a gastroenterologist at the Lahey Clinic.