MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures
With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly.
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CHARMed collaboration creates a potent therapy candidate for fatal prion diseases
A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.
Blood cell family trees trace how production changes with aging
Jonathan Weissman and collaborators developed a tool to reconstruct human cell family trees, revealing how blood cell production changes in old age.
A cool path to disease deceleration
MIT PhD student Kathrin Kajderowicz is studying how hibernation-like states could pave the way for new hypothermic therapies.
Focus on function helps identify the changes that made us human
A new approach for identifying significant differences in gene use between closely-related species provides insights into human evolution.
Six from MIT awarded 2023 Paul and Daisy Soros Fellowships for New Americans
Fellowship funds graduate studies for outstanding immigrants and children of immigrants.
Uncovering how cells control their protein output
Gene-Wei Li investigates the rules that cells use to maintain the correct ratio of the proteins they need to survive.
A “door” into the mitochondrial membrane
Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.
Robert Langer wins BBVA Foundation Frontiers of Knowledge Award
Institute Professor honored for groundbreaking work in nucleic acid delivery and nanoparticles.
New CRISPR-based map ties every human gene to its function
Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
Tracing a cancer’s family tree to its roots reveals how tumors grow
Family trees of lung cancer cells reveal how cancer evolves from its earliest stages to an aggressive form capable of spreading throughout the body.
2022 MacVicar Faculty Fellows named
Professors Kamrin, Lang, McGee, and Shoulders are honored for exceptional undergraduate teaching.
New computational tool predicts cell fates and genetic perturbations
The technique can help predict a cell’s path over time, such as what type of cell it will become.
Using CRISPR as a research tool to develop cancer treatments
KSQ Therapeutics uses technology created at MIT to study the role of every human gene in disease biology.
An on-off switch for gene editing
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.