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Cartoon illustration of a ribosome farmer near mitochondria selling colorful "organic" and "locally translated" proteins in cartons

Locally produced proteins help mitochondria function

Researchers developed an approach to study where proteins get made, and characterized proteins produced near mitochondria, gaining potential insights into mitochondrial function and disease.

August 27, 2025

Excerpt of a bar graph, with 8 bars each consisting of varying length sections of different colors

Mapping cells in time and space: New tool reveals a detailed history of tumor growth

Researchers developed a tool to recreate cells’ family trees. Comparing cells’ lineages and locations within a tumor provided insights into factors shaping tumor growth.

July 30, 2025

An illustration of the liver overlaying circles representing cells

New method combines imaging and sequencing to study gene function in intact tissue

The approach collects multiple types of imaging and sequencing data from the same cells, leading to new insights into mouse liver biology.

June 30, 2025

Three people stand in Killian Court with Great Dome in background.

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures

With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly.

December 17, 2024

Illustration of a charm bracelet with research-themed charms: DNA, neuron, viral capsid, zinc finger, light switch

CHARMed collaboration creates a potent therapy candidate for fatal prion diseases

A new gene-silencing tool shows promise as a future therapy against prion diseases and paves the way for new approaches to treating disease.

June 27, 2024

Image of bone marrow cells overlayed on an illustration of tree

Blood cell family trees trace how production changes with aging

Jonathan Weissman and collaborators developed a tool to reconstruct human cell family trees, revealing how blood cell production changes in old age.

January 31, 2024

Portrait photo of Kathrin "Kat" Kajderowicz leaning against a railing

A cool path to disease deceleration

MIT PhD student Kathrin Kajderowicz is studying how hibernation-like states could pave the way for new hypothermic therapies.

August 4, 2023

Illustration of 7 primate species in a tree with a brain-shaped canopy, with a chimp and human resembling Jane Goodall facing each other at the top

Focus on function helps identify the changes that made us human

A new approach for identifying significant differences in gene use between closely-related species provides insights into human evolution.

July 6, 2023

Two by three grid of headshots of fellowship winners against a white background

Six from MIT awarded 2023 Paul and Daisy Soros Fellowships for New Americans

Fellowship funds graduate studies for outstanding immigrants and children of immigrants.

April 25, 2023

Gene Wei Li smiles and sits on green-tinted rocks inside a building at MIT. Windows and lights are in the background.

Uncovering how cells control their protein output

Gene-Wei Li investigates the rules that cells use to maintain the correct ratio of the proteins they need to survive.

January 4, 2023

An illustration of a mitochondrion with a doorway into its membrane and a line of proteins leading in

A “door” into the mitochondrial membrane

Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.

October 25, 2022

Robert Langer, Drew Weissman, and Katalin Karikó hold paper awards on a stage, while several people seated behind them clap

Robert Langer wins BBVA Foundation Frontiers of Knowledge Award

Institute Professor honored for groundbreaking work in nucleic acid delivery and nanoparticles.

June 17, 2022

Orange-tinted pattern of horizontal and vertical lines. At far left, a sequence of lines in many colors. Superimposed on the image is a white stick figure of a human.

New CRISPR-based map ties every human gene to its function

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

June 9, 2022

Two circular phylogenetic trees, with red, blue, and black branches. Along the outside are bars of different colors — green, red, purple, et cetera

Tracing a cancer’s family tree to its roots reveals how tumors grow

Family trees of lung cancer cells reveal how cancer evolves from its earliest stages to an aggressive form capable of spreading throughout the body.

May 5, 2022

Images of the four 2022 MacVicar Faculty Fellows

2022 MacVicar Faculty Fellows named

Professors Kamrin, Lang, McGee, and Shoulders are honored for exceptional undergraduate teaching.

March 11, 2022

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