Lung cancers can use two different mechanisms to evade KRAS-inhibiting drugs
Some tumor cells develop resistance by amplifying the KRAS gene, while others change their tumor type, MIT researchers have found.
Koch Institute
New formulation helps RNA vaccines withstand high temperatures
MIT engineers have found a way to stabilize the lipid nanoparticles used to deliver RNA vaccines, which could allow the vaccines to be more widely distributed.
Biologists identify a cellular pathway that allows colorectal cancer to metastasize
They also found that obesity may put patients at higher risk for activation of the pathway. Drugs that block the pathway may help prevent metastasis.
New cell-collection device could improve early cancer detection
MIT researchers developed a handheld system that gently collects living cells from patient samples to aid cancer testing and development of personalized medicines.
Finding purpose through research
This summer, BSG-MSRP-Bio student Marina Milea investigated how lung cancers become resistant to targeted therapies, gaining hands-on research experience in the Jacks Lab at the Koch Institute.
Cells use a little-known molecule to protect themselves from iron overload
This discovery points toward new combination strategies against cancer, and may explain the iron buildup seen in disorders such as early-onset Parkinson’s disease.
Cell-preservation technique could make CAR-T cell therapy more accessible
MIT researchers’ approach, which uses naturally occurring sugars as antifreeze, could make it easier for hospitals to deploy this type of cancer treatment.
Drug that targets an inflammatory enzyme could help prevent lung cancer
A new study by MIT researchers shows that inhibiting caspase-1 can reduce the risk of tumor growth.
High-speed microscopy reveals electrical activity across the brain
The new technique could help scientists learn how the entire brain works to generate decisions and emotions.
Scientists unveil more than 600 new tissue models of human cancer
Derived from patient tumor samples and available to researchers around the world, the cells will aid the development of new cancer treatments.
MIT Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86
Tonegawa made landmark discoveries about how the immune system generates antibody diversity and how the brain forms memories.
Ketogenic diets may increase cancer risk in the small intestine
MIT researchers have found that a ketogenic high-fat, low-carbohydrate diet fuels the growth of intestinal tumors.
Two MIT faculty members named 2026 Pew Biomedical Scholars
Cell biologist Whitney Henry and immunologist Harikesh Wong will receive four years of flexible funding to advance early-career research on ferroptosis and immune decision-making.
Past participants are now the leaders of MIT’s dynaMIT Club
How the program's biggest fans came full circle and took the helm.
A new vaccine adjuvant could make it easier to eradicate polio
The adjuvant can help the injectable polio vaccine induce a strong immune response in the GI tract, which is considered critical to eradicating the virus.