Circuit that focuses attention brings in wide array of inputs
With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function.
Picower Institute for Learning and Memory
A single memory is stored across many connected brain regions
Innovative brain-wide mapping study shows that an “engram,” the ensemble of neurons encoding a memory, is widely distributed and includes regions not previously realized.
Aging Brain Initiative awards fund five new ideas to study, fight neurodegeneration
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.
School of Science announces 2022 Infinite Mile Awards
Seven staff members are recognized for their dedication to the School of Science and to MIT.
Emery Brown earns American Institute for Medical and Biological Engineering Pierre Galletti Award
AIMBE's highest honor recognizes MIT professor's contributions to neural signal processing, anesthesiology advances.
Neurons are fickle. Electric fields are more reliable for information.
Electric fields may represent information held in working memory, allowing the brain to overcome “representational drift,” or the inconsistent participation of individual neurons.
3 Questions: Emery Brown on improving anesthesia with neuroscience
Professor describes a new research center he is working to develop where researchers will seek to improve patient care by integrating neuroscience and anesthesiology.
Research advances technology of AI assistance for anesthesiologists
A new deep-learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general anesthesia could augment patient monitoring.
A new atlas of cells that carry blood to the brain
Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease.
“Traveling” nature of brain waves may help working memory work
The act of holding information in mind is accompanied by coordination of rotating brain waves in the prefrontal cortex, a phenomenon that may convey specific advantages, a new study suggests.
School of Science announces 2022 Infinite Expansion Awards
Eight postdocs and research scientists within the School of Science honored for contributions to the Institute.
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state
Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.
Research finds potential mechanism linking autism, intestinal inflammation
Infection during pregnancy with elevated levels of the cytokine IL-17a may yield microbiome alterations that prime offspring for aberrant immune responses, mouse study suggests.
Study reveals a protein’s key contribution to heterogeneity of neurons
Tomosyn’s tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction.
Feast or forage? Study finds circuit that helps a brain decide
By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states.