Broad Institute of MIT and Harvard
Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.
Awards support high-risk, high-impact research from early-career investigators.
Prokaryotes can detect hallmark viral proteins and trigger cell death through a process seen across all domains of life.
The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer.
Alex Shalek’s technologies for single-cell RNA profiling can help dissect the cellular bases of complex diseases around the globe.
Award provides five years of funding and access to a community of innovative scholars and leaders in science and technology.
The five-year collaboration aims to accelerate the translation of breakthrough engineering and biology for human health.
Innovative brain-wide mapping study shows that an “engram,” the ensemble of neurons encoding a memory, is widely distributed and includes regions not previously realized.
Researchers create a mathematical framework to examine the genome and detect signatures of natural selection, deciphering the evolutionary past and future of non-coding DNA.
Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease.
The technique can help predict a cell’s path over time, such as what type of cell it will become.