Researchers at the McGovern and Broad Institutes have developed a bacterial "nanosyringe" that can inject large proteins into specific cells in the body, which could lead to safer and more effective treatments for a variety of conditions, including cancer, reports Michael Le Page for New Scientist. “The fact that this can load a diversity of different payloads of different sizes makes it unique amongst protein delivery devices,” says graduate student Joseph Kreitz.
Ingrid Wickelgren at Scientific American highlights a new study from researchers at the McGovern and Broad Institutes, in which they used a bacterial ‘nanosyringe’ to inject large proteins into human cells. “The syringe technology also holds promise for treating cancer because it can be engineered to attach to receptors on certain cancer cells,” writes Wickelgren.
IEEE Pulse reporter Leslie Mertz spotlights Prof. Ed Boyden’s work on refining expansion microscopy. “My hope for expansion, looking 5 or 10 years out, is that it could help produce a map of molecules that is detailed enough to help us understand life itself,” says Boyden.
Prof. Li-Huei Tsai and Prof. Ed Boyden co-founded Cognito Therapeutics after their research found that gamma waves could help clear amyloid plaques, which are known to appear in Alzheimer’s patients, reports Ryan Cross for The Boston Globe. “It was the most surprising result I’ve ever got in my life,” says Tsai. “When we published our first paper, most people said, ‘I don’t believe it. This is too good to be true. How can something this simple have this kind of effect?’”
MIT has ranked first in 11 different academic fields in the latest QS World University Rankings, reports Michael T. Nietzel for Forbes.
In an excerpt from “Your Brain on Art” published in Fast Company, Susan Magsamen and Ivy Ross spotlight Prof. Li-Huei Tsai research exploring whether gamma oscillations from light and sound could help ease Alzheimer’s symptoms. “Li-Huei believes that increased gamma oscillations in the brain engage many different systems and cell types,” write Magsamen and Ross. “Because of this, the gamma waves may help with amyloid removal.”
MIT scientists have uncovered evidence that wildfire smoke particles can lead to chemical reactions in the atmosphere that erode the ozone layer, reports Margaret Osborne for Smithsonian Magazine. “From a scientific point of view, it’s very exciting to see this brand new effect,” says Solomon. “From a planetary point of view… it would be just tragic to have mankind screw up solving the ozone hole by deciding that we’re going to [allow] a lot more of these fires if we don’t mitigate climate change.”
Postdoc Saverio Cambioni speaks with Andrew Corselli of Tech Briefs about NASA’s DART mission, which was aimed at testing a method to protect Earth in case of an asteroid impact threat. “DART showed that it is technologically possible to intercept and impact a sub-kilometer asteroid, with limited prior knowledge of its shape and surface properties,” Cambioni explains.
Researchers from MIT have found that wildfire smoke can activate chlorine-containing molecules that destroy the ozone layer, writes Donna Lu for The Guardian. “The question in my mind is: is the man-made chlorine going to get … diluted and destroyed out of the atmosphere faster than global climate change is going to increase the frequency and intensity of this kind of fire?” says Prof. Susan Solomon. “I think it’s going to be a race.”
Axios reporter Jacob Knutson highlights a new study by MIT researchers that finds the smoke released by major wildfires likely reactive chlorine-containing molecules in the atmosphere, delaying the recovery of the hole in the ozone layer. The researchers developed a model that found smoke released by Australian wildfires “chemically depleted between 3% to 5% of the total ozone column in the Southern Hemisphere mid-latitudes in June and July of 2020.”
New Scientist reporter James Dinneen writes that a new study by MIT researchers finds the smoke from Australian wildfires “may have enabled hydrochloric acid to dissolve at higher temperatures, generating more of the reactive chlorine molecules that destroy ozone.” Research scientist Kane Stone explains that “satellite observations showed chemistry that has never been seen before.”
MIT scientists have found that the Australian wildfires in 2019 and 2020 unleashed remnants of chlorine-containing molecules in the stratosphere, expanding the ozone hole and suggesting that more frequent wildfires could threaten the ozone hole’s recovery, reports Dyani Lewis for Nature. “It’s like a race,” says Prof. Susan Solomon. “Does the chlorine decay out of the stratosphere fast enough in the next, say, 40–50 years that the likely increase in intense and frequent wildfires doesn’t end up prolonging the ozone hole?”
Lucy Jones PhD ’81 speaks with CBS reporter Danya Bacchus about her career in seismology, how she helped transform earthquake policy and her work creating the Great ShakeOut, drills aimed at helping people prepare for earthquakes. “I want to be remembered as a scientist, rather than just a communicator,” says Jones, “but a scientist who cared about the science getting used.”
Daily Beast reporter Meredith Bagby spotlights the life of Ron McNair PhD ’76 and his legacy as one of NASA’s first black astronauts. “Astronaut, saxophonist, and karate black belt Ron McNair overcame an impoverished childhood in segregated Lake City, South Carolina to earn a Ph.D. in physics from MIT and become one of NASA’s first Black astronauts,” writes Bagby. “Although Ron’s path to NASA was nearly derailed because of systematic racism and inequality, he found inspiration in the Black leaders around him and persevered.”
Prof. Emerita Nancy Hopkins speaks with ABC News about her work advocating for gender equality in academia and "The Exceptions: Nancy Hopkins, MIT, and the Fight for Women in Science,” a new book by Kate Zernike, a journalist who originally covered Hopkins’ efforts for The Boston Globe. Hopkins notes that when Zernike’s article was published, “this deluge happened. I mean, it was just overwhelming. And women were writing from all over the country and the world and saying, thank you. Thank you for telling the story. It's my story.”