MIT intellectual property

Researchers at MIT have developed microscopic devices that “can travel autonomously through the blood and provide electrical stimulation to precise brain regions,” and could one day be used to treat brain diseases, mental illness, or other parts of the body, reports Zoe Kriegler for Medical Design & Outsourcing. The development of microscopic wireless electronic devices (SWEDs) could “eliminate the need for brain surgery in some cases, decreasing the risk to the patient and the expense of the procedure by hundreds of thousands of dollars,” Kriegler explains. 

Prof. Deblina Sarkar speaks with Forbes reporter William A. Haseltine about her work developing “circulatronics,” microscopic electronics devices that could one day be used to help treat brain diseases. “What we have developed are tiny electronic devices that can travel through body fluids and autonomously find their target regions, with no external guidance or imaging,” explains Sarkar. “They provide very precise electrical stimulation of neurons without the need for surgery.” 

Leah Ellis, a former MIT postdoc and co-founder of MIT startup Sublime Systems, speaks with Nature reporter Jacqui Thornton about the creation of the company. “I felt that the word Sublime encapsulated the spirit of excellence, transcendence and purity that we intend to exemplify as we build a technology and a company that we hope will change the world — and the inherent properties of cement itself.” 

Prof. Pierre Azoulay speaks with WBUR’s Martha Bebinger about a new study examining the potential impact of NIH budget cuts on the development of new medicines. Azoulay and his colleagues found that “more than half of drugs approved by the FDA since 2000 used NIH-funded research that would likely not have happened if the NIH had operated with a 40% smaller budget,” Bebinger explains. 

Fierce Biotech reporter Darren Incorvaia writes that a new study by MIT researchers demonstrates how potential NIH budget cuts could endanger the development of new medications. The researchers found that if the NIH budget had been 40% smaller from 1980 to 2007, the level of NIH cuts currently being proposed, “the science underlying numerous drugs approved in the 21st century would not have been funded,” Incorvaia explains. The findings suggest that “massive cuts of the kind that are being contemplated right now could endanger the intellectual foundations of the drugs of tomorrow,” explains Professor Pierre Azoulay. 

A new study co-authored by MIT researchers finds that more than half of the drugs approved by the FDA since 2000 are connected to NIH research that would be impacted by proposed 40 percent budget cuts, reports Genetic Engineering & Biotechnology News. 

Leah Ellis, a former MIT postdoc and co-founder of MIT startup Sublime Systems, speaks with Nature reporter Emma Ulker about the company’s mission to reduce carbon emissions from cement production, how her work with co-founder Prof. Yet-Ming Chiang helped inspire her entrepreneurial journey, and her philosophy as a science entrepreneur. “At Sublime, we are tackling a hard problem — pun intended — because the cement industry is one of the most difficult to approach, owing to its sheer scale,” explains Ellis. “The motivation for our work is that change in cement-making technology has a significant impact — it’s really only once in a millennium that you get to rethink such a foundational and monumental building material.”

STAT reporter Damian Garde spotlights alumna Lita Nelson, who led MIT’s TLO for 23 years. Garde notes that Nelsen, “shattered the glass ceiling for women in tech transfer,” and Katharine Ku, head of Stanford’s Office of Technology Licensing, adds that she has been “a beacon for the tech transfer community.”

Alumna Michelle Lee, director of the USPTO, speaks with Radio Boston’s Anthony Brooks during a trip to Boston to speak at MIT about patents and innovation. Lee noted her commitment to encouraging more females to pursue STEM fields because “you never know who’s going to start that next company that’s going to revolutionize the world.”