Prof. Linda Griffith has created a “complex platform where researchers can put up to 10 organ tissues in separate compartments, regulating the flow of substances and medications between them in real time,” to determine how each organ will react, writes Devin Coldewey for TechCrunch. The scale of this model “represents a huge jump in the capabilities of this kind of system.”
Prof. Linda Griffith has developed ten miniature models of human organs “to create the closest we’ve come yet to a human-on-a-chip,” writes Jessica Hamzelou for New Scientist. “This is still only a minimal representation of a human,” said Griffith, but this kind of system could eventually eliminate the need for animal testing.
MIT researchers have developed a new capsule that allows HIV medication to be delivered over the course of a week, and could allow patients to forgo daily pills, reports Ed Cara for Gizmodo. Researchers also found that using this method for the pre-exposure pill, “would manifest in approximately a 20 per cent increase in efficacy” for weekly dosage compared to the daily regimen.
MIT researchers have developed a new slow-release capsule that could free HIV patients from having to take a daily dose of medication, according to the BBC. “Changing a medication so it only needs to be taken once a week rather than once a day should be more convenient and improve compliance,” explains research affiliate Giovanni Traverso.
UPI reporter Alan Mozes writes that MIT researchers have developed a new capsule that could be used to deliver a week’s worth of HIV medications in a single dose. “The new pill sits in the stomach for a full week, as each of seven pill compartments opens up, one-by-one, to deliver a 24-hour dose of three HAART drugs,” Mozes explains.
CBS Boston spotlights how Portal Instruments, an MIT startup, is bringing a needle-free injector to the market, which could change the way people take medicine. The device, “fires a pressurized spray to penetrate the skin, instead of piercing the skin with traditional needles.”
In a Boston Globe Magazine article about bioelectronic medicine, writer Jessie Scanlon highlights research by Profs. Ed Boyden and Daniela Rus. Boyden notes that by creating light-sensitive molecules, which can be switched on and off and inserted into neurons, “groups in academia and industry are using the tool to discover patterns of neural activity.”
Boston Globe reporter Alyssa Meyers writes that a new study by MIT researchers shows that probiotics could be used to help fight high blood pressure. The researchers found that probiotics, “can boost beneficial bacteria in the human gut that prevent pro-inflammatory immune cells from increasing in number." Pro-inflammatory immune cells have been linked with hypertension.
Using nanotechnology and CRISPR, Prof. Daniel Anderson has turned off a cholesterol-related gene in mouse liver cells, reports Julie Steenhuysen for Reuters. This new development “could lead to new ways to correct genes that cause high cholesterol and other liver diseases,” Steenhuysen writes.
BostInno’s Karis Hustad spotlights how Solve tackles some of the world’s most pressing challenges. “You need a different type of innovation or technology or adaptation and affordability of technology for some of the big challenges of today,” explains Alexandra Amouyel, Solve's executive director. “To do that, you need a much more bottom up, grassroots innovation process.”
In an article published by The Wall Street Journal about the future of programmable materials, Kelly and Zach Weinersmith highlight Prof. Daniela Rus’ work developing “origami bots that can shape themselves into tools to perform medical procedures or deliver drugs inside the body.”
In an article published by U.S. News & World Report, Robert Preidt writes that MIT researchers have identified a mechanism that helps the flu viruses evolve rapidly. “Blocking flu viruses from using the host cells' chaperones could help prevent the viruses from developing resistance to existing drugs and vaccines,” says Preidt.
MIT researchers have developed a portable paper-based test that can diagnose the Zika virus and differentiate between four types of the Dengue virus, writes Rowan Walrath for Boston Magazine. The researchers are, “also working on a diagnostic for the tick-borne Powassan virus, which…causes a severe form of encephalitis.”
A new blood test developed by MIT researchers can distinguish between the Zika and dengue viruses, reports Andrew Joseph for STAT. “Being able to distinguish the four serotypes is very important for epidemiology purposes and to know what viruses are circulating in an environment,” explains Prof. Lee Gehrke.
Prof. Lee Gehrke speaks with WBUR’s Carey Goldberg about a new paper-based diagnostic that can detect the Zika virus. “Our technology for screening large numbers of antibodies against a panel of closely related viral proteins has allowed us to specifically identify antibodies that recognize only one of the viral antigens, and that gives us a great deal of specificity.”