Boston Magazine reporter Jamie Ducharme writes that MIT researchers have found that blocking the HDAC2 enzyme may potentially reverse memory loss in Alzheimer’s patients. The researchers, “blocked HDAC2 activity by preventing it from binding with Sp3, a protein coding gene that the team found to be a crucial part of genetic blockade formation.”
TechCrunch reporter Brian Heater spotlights a new device developed by MIT researchers that can wirelessly monitor sleep. “Thanks to new AI technology, the system is now able to translate subtle movement into meaningful information about the subject’s sleep patterns, including sleep stages (light/deep/R.E.M.), movement and breathing rate."
MIT researchers have developed a new device that can track sleep patterns using radio waves, reports Alyssa Meyers for The Boston Globe. The researchers plan to “use the device to study how Parkinson’s disease affects sleep,” Meyers explains, adding that it could also be helpful with, “studying Alzheimer’s disease, insomnia, sleep apnea, and epilepsy.”
Boston Magazine reporter Jamie Ducharme writes that MIT researchers have developed a non-invasive technique for assessing cells, which could eventually be used to help diagnose diseases. The researchers are “working with doctors at Massachusetts General Hospital, who hope to use the technique to study diseases such as cancer and asthma.”
Scientific American reporter Lindsay Brownell writes that MIT researchers have developed a technique to enlarge pathology samples. “Not only are expanded samples easier to see because they are larger and more transparent, fluorescent tags and other labels can also be added to track individual molecules of interest.”
MIT researchers have developed a new way to grow liver tissue, writes Jamie Ducharme for Boston Magazine. “These minuscule structures expanded to 50 times their starting size,” Ducharme explains, “and performed normal liver functions like metabolism regulation, bile production, and detoxification.”
New York Times reporter Austin Frakt writes that MIT researchers have found that hospitals that spend more on emergency care had better patient outcomes. “Hospitals that score well on patient satisfaction, follow good processes of care and record lower hospital mortality rates,” says Prof. Joseph Doyle, “do seem to keep patients alive and out of the hospital longer.”
MIT researchers have engineered an expandable liver from human liver cells that can grow up to 50 times its original size, reports Lindsay Kalter for the Boston Herald. In the future, the researchers would like to make the expandable livers smarter, “by embedding sensors in them to tell us how they are doing,” explains Prof. Sangeeta Bhatia.
MIT researchers have developed a new way to engineer liver tissue that involves implanting tiny “seeds” of liver tissue, which expand to perform normal liver functions, reports Robert Preidt for U.S. News & World Report. The technique could one day “help reduce long wait lists for liver transplants.”
In this Bloomberg TV video aired during the July 4th Spectacular, Profs. Sangeeta Bhatia and Robert Langer discuss the Greater Boston area’s prowess in medical research. Langer explains that for his research, which is focused on inventing, “new things in chemical engineering that can change people’s lives in medicine, there is no better place.”
Jamie Ducharme of Boston Magazine highlights MIT research that increases the resolution and quality of brain scans. The team’s algorithm could fill in missing data from a scan with new pixels, thereby creating a “research-quality image,” explains Ducharme.
Graduate student Shriya Srinivasan speaks with Ira Flatow of PRI’s Science Friday about the surgical technique she and her colleagues developed to make prosthetic limbs feel more natural. Srinivasan explains that the technique allows patients to have, “finer prosthetic control — and be able to modulate position, velocity, and stiffness of prosthetic devices, which is a significant improvement to the clinical standard.”
During a panel discussion during the Koch Institute’s 16th Annual Cancer Research Symposium, participants discussed how the convergence of biology and engineering could accelerate treatments for cancer and other diseases, writes Robert Weisman for the Boston Globe. “To my mind, this is the 21st century’s innovation story,” said President Emerita Susan Hockfield.
Anne Pycha of Scientific American writes about three new methods that could be used to help detect Parkinson’s disease and enable early intervention. A new typing test developed by MIT researchers could be used to identify individuals with possible signs of Parkinson’s, “by analyzing key hold times (the time required to press and release a key).”
Susan Erdman, a principal research scientist at MIT and assistant director of MIT’s Division of Comparative Medicine, writes for STAT about her research examining whether the microbiome helped drive human evolution. “Thanks to our growing understanding of the human microbiome, it could represent a thrilling example of evolutionary symbiosis that has mutually benefitted humans and their microbial passengers.”