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STAT

Prof. Gio Traverso and his colleagues at Caltech and NYU have developed a smart ingestible sensor that may offer a less invasive way to diagnose gastrointestinal disorders. “The hope is the device will allow doctors, armed with the exact location of a GI tract disruption, to better target care — and give patients a diagnostic option they can use at home,” reports Lizzy Lawler for STAT.

TechCrunch

Researchers from MIT and Caltech have developed a pill-shaped ingestible sensor that can be monitored as it moves through the GI tract, allowing doctors to more easily diagnose gastrointestinal disorders, reports Brian Heater for TechCrunch. “The ability to characterize motility without the need for radiation, or more invasive placement of devices, I think will lower the barrier for people to be evaluated,” says Prof. Giovanni Traverso.

CBS Boston

Researchers at MIT and Massachusetts General Hospital have developed “Sybil” – an artificial intelligence tool that can predict the risk of a patient developing lung cancer within six years, reports Mallika Marshall for CBS Boston. 

The Washington Post

MIT researchers have developed a new AI tool called Sybil that could help predict whether a patient will get lung cancer up to six years in advance, reports Pranshu Verma for The Washington Post.  “Much of the technology involves analyzing large troves of medical scans, data sets or images, then feeding them into complex artificial intelligence software,” Verma explains. “From there, computers are trained to spot images of tumors or other abnormalities.”

National Geographic

National Geographic reporter Maya Wei-Haas explores how the ancient art of origami is being applied to fields such a robotics, medicine and space exploration. Wei-Haas notes that Prof. Daniela Rus and her team developed a robot that can fold to fit inside a pill capsule, while Prof. Erik Demaine has designed complex, curving fold patterns. “You get these really impressive 3D forms with very simple creasing,” says Demaine.

Nature

A review led Prof. Marzyeh Ghassemi has found that a major issue in health-related machine learning models “is the relative scarcity of publicly available data sets in medicine,” reports Emily Sohn for Nature.

HealthDay News

A study by Prof. Amy Finkelstein finds that physicians and their families are less likely to comply with medication guidelines, reports Dennis Thompson for HealthDay. The researchers found that “people tend to adhere to medication guidelines about 54% of the time, while doctors and their families lag about 4 percentage points behind that.”

Scientific American

MIT scientists have developed a miniature antenna that could one day be used to help safely transmit data from within living cells “by resonating with acoustic rather than electromagnetic waves,” reports Andrew Chapman for Scientific American. “A functioning antenna could help scientists power, and communicate with, tiny roving sensors within the cell,” writes Chapman, “helping them better understand these building blocks and perhaps leading to new medical treatments.”

Time

A stamp-sized reusable ultrasound sticker developed by researchers in Prof. Xuanhe Zhao’s research group has been named one of the best inventions of 2022 by TIME. “Unlike stretchy existing ultrasound wearables, which sometimes produce distorted images, the new device’s stiff transducer array can record high-resolution video of deep internal organs (e.g. heart, lungs) over a two-day period,” writes Alison Van Houten.

New York Times

A study by Prof. Emery Brown suggests that the combination of Covid-19 and anesthesia could prompt the human brain into a state of quiet that can last weeks or months, similar to how turtles quiet their neurons to survive winter, reports Carl Zimmer for The New York Times. The findings “might point to new ways to save people from brain damage: by intentionally putting people into this state, rather than doing so by accident.”

Wired

Research from Synlogic, a biotech company founded by Profs James Collins and Timothy Lu, has found that it’s the company’s engineered bacteria could provide some benefit to patients with a rare genetic disease, reports Emily Mullin for Wired. “Similar to how you might program a computer, we can tinker with the DNA of bacteria and have them do things like produce a drug at the right time and the right place, or in this case, break down a toxic metabolite,” says Lu.

Associated Press

Principal research scientist Leo Anthony Celi speaks with Associated Press reporter Maddie Burakoff about how pulse oximeters can provide inaccurate readings in patients of color. Celi highlights how oxygen levels can also be measured by drawing blood out of an artery in the wrist, the “gold standard” for accuracy, but a method that is a a bit trickier and more painful. 

Fortune

Jamie Karraker BS ’12 MS ’13 co-founded Alto Pharmacy – a full-service, online pharmacy that aims to create a transparent, straightforward and user-friendly experience, reports Erika Fry for Fortune. “All patients need to do after seeing their doctor is interface with the app (or via text) and pick up the prescription from their front door,” writes Fry.

Boston Business Journal

Landmark Bio, a cell and gene therapy manufacturing company co-founded by MIT and a number of other institutions, is focused on accelerating access to innovative therapies for patients, reports Rowan Walrath for Boston Business Journal. "Landmark's new facility includes laboratory space for research and early-stage drug development, as well as analytics tools,” writes Walrath. 

The Boston Globe

MIT and a number of other local institutions have launched Landmark Bio, a cell and gene therapy manufacturing firm aimed at helping small startups develop experimental therapies that are reliable, consistent, and large enough to be used in clinical trials, reports Ryan Cross for The Boston Globe.