Research Scientist Robert Ajemian, graduate student Greta Tuckute and MIT Museum Exhibit Content and Experience Developer Lindsay Bartholomew appear on The Economist’s Babbage podcast to discuss the development of generative AI. “The way that current AI works, whether it is object recognition or large language models, it’s trained on tons and tons and tons of data and what it’s essentially doing is comparing something it’s seen before to something it’s seeing now,” says Ajemian.
Research Scientists Karthik Srinivasan and Robert Ajemian speak with The Economist’s Babbage podcast about the role of big data and specialized computer chips in the development of artificial intelligence. “I think right now, actually, the goal should be just to harness big data as much as we can,” says Ajemian. “It’s kind of this new tool, a new toy, that humanity has to play with and obviously we have to play with it responsibly. The architectures that they built today are not that different than the ones that were built in the 60s and the 70s and the 80s. The difference is back then they did not have big data and tremendous compute."
Will Dunham at Reuters writes about new research from Prof. Evelina Fedorenko and others, which found that polyglots “who spoke between five and 54 languages” used less brain activity when processing their native language. "We think this is because when you process a language that you know well, you can engage the full suite of linguistic operations - the operations that the language system in your brain supports," says Fedorenko.
Prof. Feng Zhang has been named to STAT’s 2024 STATUS List, which highlights the leaders shaping the future of health and life sciences, reports Dialynn Dwyer for Boston.com. “Among the companies he’s co-founded is Editas Medicine, which as of late 2023 was now the official holder of patent rights to the CRISPR-Cas9 gene editing tool used in the sickle cell therapy Casgevy, and Aera Therapeutics, which in February 2023 raised $193 million in venture funding to develop protein nanoparticles as a way of delivering gene editing,” Dwyer writes.
Omar Abudayyeh '12, PhD '18 and Jonathan Gootenberg '13 speak with Robert Weisman at The Boston Globe about their deep-rooted working relationship, which began as undergraduates at MIT and has gone on to include joint appointments at the McGovern and Broad Institutes and multiple startups. “Science is difficult, and it’s great to have someone to do it with,” said Gootenberg. “You got to work with people you enjoy hanging out with.”
MIT researchers have used machine learning to uncover the different kinds of sentences that most likely to activate the brain’s key language processing centers, reports Kyle Wiggers and Devin Coldewey for TechCrunch. The model, “was able to predict for novel sentences whether they would be taxing on human cognition or not,” they explain.
MIT researchers have developed a new cell imaging technique that offers “the ability to observe up to seven different molecules simultaneously,” writes Amal Jos Chacko for Interesting Engineering. “This could open the door to a deeper understanding of cellular functions, aging, and diseases.”
MIT researchers have “used an algorithm to sort through millions of genomes to find new, rare types of CRISPR systems that could eventually be adapted into genome-editing tools,” writes Sara Reardon for Nature. “We are just amazed at the diversity of CRISPR systems,” says Prof. Feng Zhang. “Doing this analysis kind of allows us to kill two birds with one stone: both study biology and also potentially find useful things.”
Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li Huei Tsai, has developed a “specialized headset that delivers 40Hz auditory and visual stimulation” to the brain, which could potentially slow down the cognitive decline and neurodegeneration in Alzheimer’s disease, reports William A. Haseltine for Forbes. Prof. Li-Huei Tsai “and her team speculated that if gamma wave activity is reduced in Alzheimer’s disease, perhaps, artificially stimulating the brain may enhance synchronized firing and restore cognition,” writes Haseltine.
Cognito Therapeutics, founded by Prof. Ed Boyden and Prof. Li-Huei Tsai, is using a 40 Hzlight-flickering and auditory headset to help slow the progression of Alzheimer’s and restore cognition, reports William A. Haseltine for Forbes. “A recent pilot clinical trial found that this technology is not only safe and tolerable for home use, but also has a positive impact on reducing symptoms associated with age-related neurodegeneration,” writes Haseltine.
Prof. Ev Fedorenko has been studying the differences in “the neural architecture of speakers who speak languages with different properties,” reports Sofia Quaglia for Wired. “Her studies suggest that the core features of language systems in the brain seem similar across the board,” explains Quaglia.
Researchers at MIT have developed a soft robot that can be controlled by a weak magnetic field and travel through tiny spaces within the human body, reports Andrew Paul for Popular Science. “Because of their soft materials and relatively simple manipulation, researchers believe such mechanisms could be used in biomedical situations, such as inching through human blood vessels to deliver a drug at a precise location,” explains Paul.
MIT researchers have discovered an RNA-guided DNA-cutting enzyme in eukaryotes, reports Science. “The researchers speculate that eukaryotic cells may have gained the newly identified editing genes from transposable elements—so-called jumping genes—they received from bacteria,” writes Science.
MIT researchers have identified a new biological editing system that could “potentially be even more precise than CRISPR gene editing,” reports Laura Baisas for Popular Science. The new system, based on a protein called Fanzor, is “the first programmable RNA-guided system discovered in eukaryotes,” Baisas notes.
Prof. John Gabrieli speaks with GBH host Jeremy Siegel about his research showing that standard autism diagnostic tests often prevent women and girls from receiving proper diagnosis and proper treatment. “It’s only in recent years that we've understood that autism can be expressed quite differently in females,” says Gabrieli. “And we need to know that so they get the right kind of help.”