Writing for STAT, Karen Weintraub spotlights Prof. J. Christopher Love’s work developing a new desktop drug manufacturing process that can produce thousands of doses of biopharmaceuticals on demand. “I think in the long run there’ll be an opportunity to think about manufacturing for patients in a new way,” says Love.
Boston Herald reporter Alexi Cohan highlights a new lab at MIT, led by Prof. Tyler Jacks, that will investigate how the immune system can be used to treat and manage pancreatic cancer. “In the long term we hope that the work that we are doing will help us diagnose the disease at even early stage and maybe even prevent it altogether,” Jacks explains.
Boston Globe reporter Martin Finucane writes that MIT researchers have developed sensors that can track dopamine levels in the brain. The sensors could eventually be used to monitor “Parkinson’s patients who receive a treatment called deep brain stimulation,” Finucane explains, adding that the sensors could “help deliver the stimulation only when it’s needed.”
Researchers from MIT and Brigham and Women’s Hospital have found that cellular changes lead to chronic sinus inflammation, reports Allen Cone for UPI. Cone explains that the findings could also “help patients with chronic inflammatory diseases of barrier tissues, such as asthma, eczema, and inflammatory bowel disease.”
By analyzing thousands of human cells and creating a cellular map of human barrier tissue, MIT researchers have identified the mechanism that may cause chronic allergic inflammation in the sinus, according to Xinhua News Agency. The findings could have “implications on treatment of other chronic inflammatory diseases of barrier tissues, such as asthma, eczema, and inflammatory bowel disease.”
STAT reporter Orly Nadell Farber writes about a new study by MIT researchers that shows glaucoma might be caused by T-cells, an integral component of the human body’s immune system, attacking retinal cells. Farber explains that, “this discovery could unlock a critical new door for treatment options.”
A new study by MIT researchers provides evidence that glaucoma may be caused by an autoimmune disease, according to a HealthDay News piece published by UPI. “Further research will try to determine whether other parts of the immune system play a role in glaucoma, and whether autoimmunity is a factor in degenerative brain diseases.”
STAT reporter Justin Chen writes about a new study that examines why patients with pancreatic cancer often experience significant weight loss. Prof. Matt Vander Heiden explains that the findings show, “pancreatic cancer patients clearly have a lot of tissue wasting and whether it’s good or bad, we can now say that it’s not necessarily bad at diagnosis.”
In this WBUR segment, Prof. Robert Langer speaks with Karen Weintraub about the challenges of bringing scientific discoveries from an academic lab to the marketplace. “The people who often do the best are the ones that are good at dealing with failure,” says Langer.
Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a wireless ingestible sensor that could one day be used to diagnose and treat disease. “The most exciting thing is that we can wirelessly control tiny implants even though they have no batteries at all,” says Prof. Fadel Adib.
Professors Edward Boyden and Feng Zhang have been named to the 2018 class of Howard Hughes Medical Institute investigators, reports Jonathan Saltzman for The Boston Globe. “We selected these scientists because they know how to ask hard and interesting questions with skill and intellectual courage,” says David Clapham, vice president and chief scientific officer of the institute.
A new paper co-authored by Prof. Omer Yilmaz and Prof. David Sabatini found that fasting substantially “improves stem cells' ability to regenerate,” reports Xinhua. The researchers hope this finding could lead to new drug treatments that “stimulate regeneration without requiring patients to fast, which is difficult for most people.”
Boston Herald reporter Lindsay Kalter writes that a team of MIT researchers has developed a new technique that can deliver medication to specific regions of the brain with extreme precision. “The whole idea here is that instead of treating the entire brain, you can treat small portions of the brain,” explains Prof. Michael Cima.
AP reporter Lauran Neergaard writes that MIT researchers have developed a hair-thin implant that can deliver medications to specific regions of the brain. Neergaard writes that the device, “could mark a new approach to treating brain diseases — potentially reducing side effects by targeting only the hard-to-reach circuits that need care.”
STAT reporter Dominic Smith highlights how MIT researchers are applying the art of origami to developing a new way to deliver cancer medications. Prof. Michael Cima explains that, “the idea here was, is there a way we could do a minimally invasive procedure to deploy some sort of device that will deliver the drug over that entire course of the therapy?”