Boston Globe reporter Jessie Scanlon spotlights Prof. Regina Barzilay’s work developing machine learning systems that can identify patients at risk of developing breast cancer. Barzilay is creating “software that aims to teach a computer to analyze mammogram images more effectively than the human eye can and to catch signs of cancer in its earliest phases.”
MIT researchers have developed a new technique to measure cancer cells that provides insight into how certain cells respond to treatment, reports the Xinhua news agency. The findings could be used to help develop new drug targets, making current treatments more effective.
MIT researchers have developed a new injectable material that can deliver medication through cartilage and could one day be used to help reverse osteoarthritis, reports Katie Camero for The Boston Globe. Camero explains that the new material “can penetrate deep into the tissue, delivering drugs that can potentially help the chondrocytes heal cartilage.”
STAT reporter Kate Sheridan writes about MIT startup SQZ Biotech, which is developing a “technology that will squeeze cells to open up tiny pores in their membranes to deliver gene therapies or medicines straight into the cell.”
MIT startup Lyndra has found that an ingestible device originally developed by researchers from MIT and Brigham and Women’s Hospital can help tackle the problem of medication adherence, reports Kate Sheridan for STAT. The new technology could make it possible for patients to take “one pill a week for conditions as varied as Alzheimer’s, addiction, allergies, malaria, schizophrenia, high cholesterol, and HIV.”
A team of researchers led by Prof. J. Christopher Love has developed a system to produce on-demand clinical-grade vaccines and drugs, writes Dr. Francis Collins on the NIH Director’s Blog. In addition to allowing on site production for hospitals the systems could also “produce biologic treatments specially tailored to attack the cancer of a particular individual,” suggests Collins.
Writing for STAT, Karen Weintraub spotlights Prof. J. Christopher Love’s work developing a new desktop drug manufacturing process that can produce thousands of doses of biopharmaceuticals on demand. “I think in the long run there’ll be an opportunity to think about manufacturing for patients in a new way,” says Love.
Boston Herald reporter Alexi Cohan highlights a new lab at MIT, led by Prof. Tyler Jacks, that will investigate how the immune system can be used to treat and manage pancreatic cancer. “In the long term we hope that the work that we are doing will help us diagnose the disease at even early stage and maybe even prevent it altogether,” Jacks explains.
Boston Globe reporter Martin Finucane writes that MIT researchers have developed sensors that can track dopamine levels in the brain. The sensors could eventually be used to monitor “Parkinson’s patients who receive a treatment called deep brain stimulation,” Finucane explains, adding that the sensors could “help deliver the stimulation only when it’s needed.”
Researchers from MIT and Brigham and Women’s Hospital have found that cellular changes lead to chronic sinus inflammation, reports Allen Cone for UPI. Cone explains that the findings could also “help patients with chronic inflammatory diseases of barrier tissues, such as asthma, eczema, and inflammatory bowel disease.”
By analyzing thousands of human cells and creating a cellular map of human barrier tissue, MIT researchers have identified the mechanism that may cause chronic allergic inflammation in the sinus, according to Xinhua News Agency. The findings could have “implications on treatment of other chronic inflammatory diseases of barrier tissues, such as asthma, eczema, and inflammatory bowel disease.”
STAT reporter Orly Nadell Farber writes about a new study by MIT researchers that shows glaucoma might be caused by T-cells, an integral component of the human body’s immune system, attacking retinal cells. Farber explains that, “this discovery could unlock a critical new door for treatment options.”
A new study by MIT researchers provides evidence that glaucoma may be caused by an autoimmune disease, according to a HealthDay News piece published by UPI. “Further research will try to determine whether other parts of the immune system play a role in glaucoma, and whether autoimmunity is a factor in degenerative brain diseases.”
STAT reporter Justin Chen writes about a new study that examines why patients with pancreatic cancer often experience significant weight loss. Prof. Matt Vander Heiden explains that the findings show, “pancreatic cancer patients clearly have a lot of tissue wasting and whether it’s good or bad, we can now say that it’s not necessarily bad at diagnosis.”
In this WBUR segment, Prof. Robert Langer speaks with Karen Weintraub about the challenges of bringing scientific discoveries from an academic lab to the marketplace. “The people who often do the best are the ones that are good at dealing with failure,” says Langer.