Koch Institute

Prof. Emerita Mary-Lou Pardue, a cellular and molecular biologist whose work “formed the foundation for key advancements and discoveries in understanding the structure of chromosomes,” has died at age 90, reports Bryan Marquard for The Boston Globe. Pardue “was a role model of what women in science can be at a time when there weren’t a lot of those, and a trailblazer as a woman,” emphasizes Ky Lowenhaupt, manager of the Biophysical Instrumentation Facility at MIT, “but also a trailblazer as a scientist who didn’t do things along the path that other people took.”

STAT lists “The Exceptions: Sixteen Women, MIT, and the Fight for Equality in Science,” by Kate Zernicke as a “best book on health and science to check out this summer.”  The book focuses on Prof. Nancy Hopkins’ “career, which culminates in not only numerous scientific successes but also a collaborative effort with 15 other women faculty demonstrating evidence of gender discrimination at MIT,” explains STAT. “This work led to studies to address gender equity at nine other universities.” 

Prof. Sara Seager, Prof. Robert Langer and Prof. Nancy Kanwisher have been awarded the 2024 Kavli Prize for their work in the three award categories: astrophysics, nanoscience, and neuroscience, respectively, reports Michael T. Nietzel for Forbes. According to the Norwegian Academy of Science and Letters, this award honors scientists with outstanding research “that has broadened our understanding of the big, the small and the complex,” writes Nietzel. 

MIT researchers have developed new technology that allows vaccines to be directly inserted into the lymph nodes to target two of the most common mutations in the KRAS gene, which cause roughly one third of all cancers, reports Jaimie Seaton for Scientific American. “The team modified the small vaccine components to include a fatty acid, which enables the vaccine to effectively hitch a ride on albumin, a common protein found throughout the body,” explains Seaton. “Albumin serves as a molecular shuttle bus, with pockets on its surface where fatty acids can bind to it.”

Forbes contributor William Haseltine spotlights how MIT researchers developed a biosensor ingestible capsule that can gather and transmit information on a patient’s condition to a physician. Haseltine notes that “aside from respiratory and heart rate monitoring, future applications for the pill could come from alterations in its design, leading to other avenues of health monitoring. These may include digestive health, blood sugar monitoring and cancer cell detection.” 

Researchers from MIT and elsewhere are developing an electronic pill that can “measure heart rate, breathing rate and core temperature – from inside a human stomach,” reports Celia Ford for Wired. “We have a solution that’s relatively simple and enables access broadly,” says Prof. Giovanni. “I think that can be really transformative.”

MIT researchers have developed a new cell imaging technique that offers “the ability to observe up to seven different molecules simultaneously,” writes Amal Jos Chacko for Interesting Engineering. “This could open the door to a deeper understanding of cellular functions, aging, and diseases.”

Researchers from MIT and elsewhere have developed a swallowable “technopill” that can monitor vital signs from inside the body, reports Dennis Thompson for HealthDay. “The ability to facilitate diagnosis and monitor many conditions without having to go into a hospital can provide patients with easier access to healthcare and support treatment,” says Prof. Giovanni Traverso.

New Scientist reporter Alice Klein writes that MIT researchers have developed an ingestible electronic device that “can measure your breathing and heart rate from inside your gut [and] could potentially diagnose sleep apnea and even detect opioid overdoses.” The device could one day allow “people to be assessed for sleep apnea wirelessly and cheaply while at home.”

Researchers at MIT and elsewhere have developed a swallowable electronic capsule that can be used to help diagnose sleep apnea and other sleep disorders, reports Ian Randall for Newsweek. “Conventional laboratory and home sleep studies require the patient to be attached to many different sensors,” says Prof. Giovanni Traverso. “As you can imagine, trying to sleep with all of this machinery can be challenging. [The] ingestible capsule just requires that the patient swallow the vitamin-sized pill. It's easy and unobtrusive and can accurately measure both respiratory rate and heart rate while the patient sleeps."

7 News spotlights how MIT researchers have developed a new implantable device that could provide diabetes patients with insulin without using injections. “What we’ve been able to show is that with a minimally invasive implant that is sitting just under the skin, we’ve actually been able to sort of achieve a diabetic reversal,” explains Research Scientist Siddharth Krishnan.

Gizmodo reporter Ed Cara writes that MIT researchers have developed a new implantable device that can produce its own supply of insulin for up to a month. The team envisions that the device could “eventually be used for other medical conditions dependent on a regular supply of externally produced proteins, such as certain forms of anemia treated with erythropoietin,” writes Cara.

MIT researchers have developed a new implant that in the future could be used to deliver insulin to patients for up to a month, potentially enabling patients to control diabetes without injections, reports Tony Ho Tran for the Daily Beast. In the future, the researchers hope to “develop a device for humans that would be roughly the size of a stick of gum,” writes Tran. “The implant could also be used to deliver things like drugs or proteins to help treat other diseases in humans as well.”

MIT researchers at MIT have developed a microfluidic chip-based model of liver tissue that “allows researchers to understand the biological mechanisms underlying liver tissue regeneration and points to several molecules that may promote the process,” reports William A. Haseltine for Forbes. "These results mark significant progress in our understanding of the human body’s regenerative properties," writes Haseltine. 

Researchers at MIT have developed a mobile vaccine printer capable of printing a vaccine onto a patch of microneedles that can be absorbed into the skin without injection, reports Sandra Tsing for NPR. “These printed vaccines could be used in areas that are unable to refrigerate traditional vaccines,” explains Tsing.