Institute for Medical Engineering and Science (IMES)

Prof. David Sontag, Monica Agrawal PhD '23, Luke Murray SM '22, and Divya Gopinath '19, MEng '20 co-founded Layer Health - an AI healthcare startup that is applying large language models (LLMs) to help clinicians with medical chart reviews and data abstraction, reports Seth Joseph for Forbes. “The same chart review problem we’re solving with our clinical registry module is faced by clinicians at the point of care,” says Sontag. “For example, one of our next modules will focus on real-time clinical decision support to help automate clinical care pathways, leading to more reliable, high-quality care."

Researchers from MIT have “identified genes that the tuberculous bacteria rely on to survive and spread,” reports Allison DeAngelis for STAT. “Until now, very little was known about how tuberculous bacteria survived temperature changes, oxygen levels, humidity, and other environmental factors during the journey from one person’s lungs to another’s,” explains DeAngelis. 

Prof. Sarah Millholland, Prof. Christian Wolf, Prof. Emil Verner, Prof. Darcy McRose, Prof. Marzyeh Ghassemi, Prof. Mohsen Ghaffari and Prof. Ariel Furst have received the 2025 Sloan Research Fellowship for “being among the most promising scientific researchers currently working in their fields,” reports Michael T. Nietzel for Forbes. “Sloan Research Fellows are chosen in seven scientific and technical fields—chemistry, computer science, Earth system science, economics, mathematics, neuroscience, and physics,” explains Nietzel. 

Researchers from MIT and elsewhere have developed a new vaccine that “could be potentially used against a broad array of coronaviruses like the one that causes Covid-19 and potentially forestall future pandemics,” reports Alex Knapp for Forbes. “The vaccine involves attaching tiny pieces of virus that remain unchanged across related strains to a nanoparticle,” explains Knapp.

MIT Profs. Angela Belcher, Emery Brown, Paula Hammond and Feng Zhang have been honored with National Medals of Science and Technology, reports Michael T. Neitzel for Forbes. Additionally, R. Lawrence Edwards '76 received a National Medal of Science and Noubar Afeyan PhD '87, a member of the MIT Corporation, accepted a National Medal on behalf of Moderna. The recipients have been awarded “the nation’s highest honors for exemplary achievements and leadership in science and technology,” explains Neitzel. 

Prof. David Autor has been named a Senior Fellow in the Schmidt Sciences AI2050 Fellows program, and Profs. Sara Beery, Gabriele Farina, Marzyeh Ghassemi, and Yoon Kim have been named Early Career AI2050 Fellows, reports Michael T. Nietzel for Forbes. The AI2050 fellowships provide funding and resources, while challenging “researchers to imagine the year 2050, where AI has been extremely beneficial and to conduct research that helps society realize its most beneficial impacts,” explains Nietzel. 

MIT researchers have developed microneedle patches that are capable of restoring hair growth in alopecia areata patients, reports Ernie Mundell for HealthDay. The team’s approach includes a, “patch containing myriad microneedles that is applied to the scalp,” writes Mundell. “It releases drugs to reset the immune system so it stops attacking follicles.” 

Scientific American reporter Payal Dhar spotlights how MIT engineers developed a beating, biorobotic replica of the human heart that could be used to “simulate the workings of both a healthy organ and a diseased one.” The replica, "which pumps a clear fluid instead of blood, is hooked up to instruments that measure blood flow, blood pressure, and more," writes Dhar. "It’s also customizable: the user can change the heart rate, blood pressure and other parameters, then watch how these changes affect the heart’s function in real time.”

In a new paper, MIT researchers detail how they have used AI techniques to discover a class of “of antibiotics capable of killing methicillin-resistant Staphylococcus aureus (MRSA),” reports Helen Floresh for Fierce Biotech. “This paper announces the first AI-driven discovery of a new class of small molecule antibiotics capable of addressing antibiotic resistance, and one of the few to have been discovered overall in the past 60 years,” says postdoctoral fellow Felix Wong.

Researchers at MIT have used artificial intelligence to uncover, “a new class of antibiotics that can treat infections caused by drug-resistant bacteria,” reports Jeremy Hsu for New Scientist. “Our [AI] models tell us not only which compounds have selective antibiotic activity, but also why, in terms of their chemical structure,” says postdoctoral fellow Felix Wong.

7 News spotlights how MIT researchers have developed a new implantable device that could provide diabetes patients with insulin without using injections. “What we’ve been able to show is that with a minimally invasive implant that is sitting just under the skin, we’ve actually been able to sort of achieve a diabetic reversal,” explains Research Scientist Siddharth Krishnan.

Gizmodo reporter Ed Cara writes that MIT researchers have developed a new implantable device that can produce its own supply of insulin for up to a month. The team envisions that the device could “eventually be used for other medical conditions dependent on a regular supply of externally produced proteins, such as certain forms of anemia treated with erythropoietin,” writes Cara.

Prof. Regina Barzilay speaks with The Economist about how AI can help advance medicine in areas such as uncovering new drugs. With AI, “the type of questions that we will be asking will be very different from what we’re asking today,” says Barzilay.

MIT researchers have developed a new implant that in the future could be used to deliver insulin to patients for up to a month, potentially enabling patients to control diabetes without injections, reports Tony Ho Tran for the Daily Beast. In the future, the researchers hope to “develop a device for humans that would be roughly the size of a stick of gum,” writes Tran. “The implant could also be used to deliver things like drugs or proteins to help treat other diseases in humans as well.”

Researchers at MIT and elsewhere have used artificial intelligence to develop a new antibiotic to combat Acinetobacter baumannii, a challenging bacteria known to become resistant to antibiotics, reports Hannah Kuchler for the Financial Times. “It took just an hour and a half — a long lunch — for the AI to serve up a potential new antibiotic, an offering to a world contending with the rise of so-called superbugs: bacteria, viruses, fungi and parasites that have mutated and no longer respond to the drugs we have available,” writes Kuchler.