Gene changes linked to severe repetitive behaviors
Graybiel lab identifies genes linked to abnormal repetitive behaviors often seen in models of addiction and schizophrenia.
Basic cell health systems wear down in Huntington’s disease, analysis shows
A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.
Scientists seek insight into Parkinson’s, addiction by tracking gene expression in the brain
Two MIT faculty members earn funding from the G. Harold and Leila Y. Mathers Foundation.
One more clue to brain changes in Huntington’s disease
Opioid receptor MOR1 changes discovered in neurodegenerative disease model.
Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA
Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.
Alumnus gives MIT $4.5 million to establish the Broderick Fund for Phytocannabinoid Research
Gifts to MIT and Harvard Medical School totaling $9 million will fund independent research on cannabinoid’s influence on brain health and behavior.
Biologists find unexpected role for amyloid-forming protein
Yeast protein could offer clues to how Alzheimer’s plaques form in the brain.
Biology, driven by data
Newly tenured biological engineer Ernest Fraenkel goes where the numbers lead.
Possible role for Huntington’s gene discovered
Mutant forms of the gene disrupt chemical modifications that control access to genes necessary for normal brain cell function.
Protein linked to aging may boost memory and learning ability
Discovery could lead to new drugs to fight Alzheimer’s and other neurological diseases.