Health sciences and technology

The Conversation spotlights Institute Prof. Robert Langer ‘74 who spoke at the 2022 Imagine Solutions Conference about his academic career and work applying his chemical engineering background to his research in health sciences. “I learned that if you’re not your own champion, nobody else will be,” says Langer. “So, I got involved in patenting things, and my students were very interested in seeing their work make a difference… My story is sort of one person’s example of how you can try to use science to help relieve suffering and prolong life.”

Satellite Bio, a startup co-founded by Prof. Sangeeta Bhatia, aims to create “tissue implants to ‘repair, restore, or even replace’ diseased or dying organs,” reports Ryan Cross for The Boston Globe.

STAT reporter Katie Palmer spotlights Principal Research Scientist Leo Anthony Celi’s research underscoring the importance of improving the diversity of datasets used to design and test clinical AI systems. “The biggest concern now is that the algorithms that we’re building are only going to benefit the population that’s contributing to the dataset,” says Celi. “And none of that will have any value to those who carry the biggest burden of disease in this country, or in the world.”

Boston Globe reporter Michael Blanding spotlights Prof. Hugh Herr’s work with Dr. Matthew Carty in developing a new amputation surgery called agonist-antagonist myoneural interface (AMI) procedure, which reconnects muscles to amplify electrical signals sent along the nerves. “My dream as a scientist is that a person with an arm amputation could play a Beethoven piece at normal speeds and dexterity – and for legs, that a person could dance ballet,” says Herr.

Institute Prof. Robert Langer, whose “innovations have helped create more than 100 products from artificial skin to messenger RNA (mRNA) vaccines,” speaks with Guardian reporter Zoë Corbyn. “I think it’s important to stress how much engineers can and have changed the world for the better,” says Langer. “It’s a thrill for me to see engineering and biology improving people’s lives; that’s been my dream from the beginning.”

Axios reporter Erin Broadwin spotlights Dimagi, a digital tool for health workers in remote areas that was started by researchers from the MIT Media Lab and the Harvard-MIT Health Sciences and Technology program.

OPT Industries, an MIT spinoff, has created InstaSwab, a nasal swab “up to 20 times more effective in bacterial sample elution,” reports Brian Heater for TechCrunch. “With the ability to print around the clock, the firm also believes it can play a pivotal role in addressing supply chain concerns — a long-time goal for additive manufacturing,” writes Heater.

Researchers from MIT and journalists from STAT conducted a months long investigation and found that “subtle shifts in data fed into popular health care algorithms — used to warn caregivers of impending medical crises — can cause their accuracy to plummet over time, raising the prospect AI could do more harm than good in many hospitals,” reports Casey Ross for STAT.

PBS Nova premiered “Augmented,” a documentary film that features Prof. Hugh Herr and his research team’s work in developing brain controlled robotic limbs and reimagining amputation procedures. “Herr is teaming up with an injured climber and a surgeon at a leading Boston hospital to test a new approach to surgical amputation that allows prosthetic limbs to move and feel like the real thing,” writes PBS Nova.

STAT has named Noubar Afeyan ’87, Cornelia Bargmann PhD ’87, Prof. Regina Barzilay and Prof. Sangeeta N. Bhatia to their list of trailblazing researchers working in the life sciences. “Many of the STATUS List are well-known as change makers; others are largely unheralded heroes. But all have compelling stories to tell,” writes STAT.

David Lucchino ’06 and Prof. Robert Langer have co-founded Frequency Therapeutics, a biotechnology company focused on developing a new approach to restoring hearing from the most common form of hearing loss, reports Jack Kelly for Forbes. “FX-322 is designed to treat the underlying cause of SNHL (sensorineural hearing loss) by regenerating sensory hair cells through activation of progenitor cells already present in the cochlea,” writes Kelly.

Wall Street Journal reporter John Anderson spotlights “Augmented” a new PBS documentary featuring Prof. Hugh Herr and his work in robotic limbs and surgery.

A new documentary titled “Augmented” spotlights Prof. Hugh Herr and his work developing bionic limbs at the MIT Media Lab, reports Dana Gerber for The Boston Globe. “The long-term hope for the procedure is that people with Ewing amputations will be able to further adapt to the bionic limbs shown in the film, which Herr’s team is developing at MIT,” writes Gerber.

MIT researchers have developed a transparent, degradable medical dressing that could be used to help gut wounds heal more quickly and efficiently without leaking bacteria, reports Alex Wilkins for New Scientist. The researchers “designed their dressing to work like duct tape, which is only sticky on one side,” writes Wilkins. “Once it covers the wound, it quickly forms a hydrogel, an adhesive layer that can help the wound to heal.”

STAT reporters Katie Palmer and Casey Ross spotlight how Prof. Regina Barzilay has developed an AI tool called Mirai that can identify early signs of breast cancer from mammograms. “Mirai’s predictions were rolled into a screening tool called Tempo, which resulted in earlier detection compared to a standard annual screening,” writes Palmer and Ross.