Principal research scientist Leo Anthony Celi speaks with Associated Press reporter Maddie Burakoff about how pulse oximeters can provide inaccurate readings in patients of color. Celi highlights how oxygen levels can also be measured by drawing blood out of an artery in the wrist, the “gold standard” for accuracy, but a method that is a a bit trickier and more painful.
Forbes reporter Marija Butkovic spotlights Alicia Chong Rodriguez MS ’18, Founder and CEO of Bloomer Tech, for her work in building a cardiovascular disease and stroke database that can generate non-invasive digital biomarkers. “We envision a world where the future of AI in healthcare performs the best it can in women,” says Chong Rodriguez. “We also have created a digital biomarker pipeline where our digital biomarkers can explain, influence, and even improve health outcomes for women.”
Temporal thermometers may be less accurate than oral thermometers in detecting fevers among hospitalized Black patients, reports Jacqueline Howard for CNN. This “really reflects the much bigger systematic problem that we have now in the way we design, we innovate, we develop health products – not just medical devices but also medications and interventions,” says Principal Research Scientist Leo Anthony Celi. “We really need to step up in terms of making sure that the research we perform is more inclusive so that we avoid these unintended consequences of the technology that we develop.”
Researchers from MIT are working with the Staten Island Performing Provider System to develop an algorithm that can predict who in the system is at risk for an opioid overdose, reports Maddie Bender for the Daily Beast. “In preliminary testing, Conte’s team and MIT Sloan researchers found their model was highly accurate at predicting overdoses and fatal overdoses, even with delays in the data of up to 180 days,” writes Bender.
CAMP4, a startup founded by Prof. Richard Young, is developing a new class of RNA-based therapies to treat genetic diseases, reports Ryan Cross for The Boston Globe. The “startup’s experimental approach will allow it to dial up the output of genes to treat genetic diseases, with an initial focus on a severe form of epilepsy and life-threatening live diseases,” writes Cross.
Principal Research Scientist Leo Anthony Celi oversaw a study which found that people of color were given significantly less supplemental oxygen than white people because of inaccuracies in pulse oximeter readings, reports Nancy Lapid for Reuters. “Nurses and doctors make the wrong decisions and end up giving less oxygen to people of color because they are fooled [by incorrect readings from pulse oximeters],” says Celi.
Rob Morris PhD ’14 has dedicated his career to easing access to mental health services online, reports Shalene Gupta for Fast Company. “When you search for a flight on Google, you get directed to these options that make you instantly buy a flight,” he says. “The interface is beautiful. But when you look up mental health, it’s not great. I want to do for mental health what Google did for flights.”
InsideTracker - a personalized-nutrition company founded by scientists from MIT, Harvard, and Tufts University - utilizes blood tests to calculate biological age, reports Betsy Morris for The Wall Street Journal. The company analyzes blood samples for “markers of conditions like inflammation, heart health and liver or kidney disorder,” explains Morris. “Those who test as older than their years get recommendations to adjust diet, exercise and supplements.”
During the AI Cures Conference, Prof. Regina Barzilay spoke with Food and Drug Administration senior staff fellow Amir Khan about how the agency intends to regulate artificial intelligence in medicine, reports Casey Ross for STAT. “’My thinking is that models should be regulated based on their functionality, and not necessarily on the input data they use,” said Barzilay.
The Conversation spotlights Institute Prof. Robert Langer ‘74 who spoke at the 2022 Imagine Solutions Conference about his academic career and work applying his chemical engineering background to his research in health sciences. “I learned that if you’re not your own champion, nobody else will be,” says Langer. “So, I got involved in patenting things, and my students were very interested in seeing their work make a difference… My story is sort of one person’s example of how you can try to use science to help relieve suffering and prolong life.”
Satellite Bio, a startup co-founded by Prof. Sangeeta Bhatia, aims to create “tissue implants to ‘repair, restore, or even replace’ diseased or dying organs,” reports Ryan Cross for The Boston Globe.
STAT reporter Katie Palmer spotlights Principal Research Scientist Leo Anthony Celi’s research underscoring the importance of improving the diversity of datasets used to design and test clinical AI systems. “The biggest concern now is that the algorithms that we’re building are only going to benefit the population that’s contributing to the dataset,” says Celi. “And none of that will have any value to those who carry the biggest burden of disease in this country, or in the world.”
Boston Globe reporter Michael Blanding spotlights Prof. Hugh Herr’s work with Dr. Matthew Carty in developing a new amputation surgery called agonist-antagonist myoneural interface (AMI) procedure, which reconnects muscles to amplify electrical signals sent along the nerves. “My dream as a scientist is that a person with an arm amputation could play a Beethoven piece at normal speeds and dexterity – and for legs, that a person could dance ballet,” says Herr.
Institute Prof. Robert Langer, whose “innovations have helped create more than 100 products from artificial skin to messenger RNA (mRNA) vaccines,” speaks with Guardian reporter Zoë Corbyn. “I think it’s important to stress how much engineers can and have changed the world for the better,” says Langer. “It’s a thrill for me to see engineering and biology improving people’s lives; that’s been my dream from the beginning.”
Axios reporter Erin Broadwin spotlights Dimagi, a digital tool for health workers in remote areas that was started by researchers from the MIT Media Lab and the Harvard-MIT Health Sciences and Technology program.