MIT researchers have developed Boltz-2, an AI algorithm “that unites protein folding and prediction of small-molecule binding affinity in one package,” reports Laura Howes for Chemical & Engineering News. “The researchers say their new AI model approaches the level of accuracy achieved by traditional computational chemistry—such as methods involving free-energy perturbation calculations—but much more quickly and cheaply,” explains Howes.
Kurt Knutsson of FOX News spotlights how MIT researchers have developed a new mobile robot, dubbed E-BAR, designed to help physically support the elderly and prevent falls at home. “What stands out about E-BAR is how it's designed with real people in mind, not just as a tech gadget,” Knutsson explains. “It's easy to see how something like this could make a big difference for seniors wanting to stay independent without feeling tied down by bulky or uncomfortable devices.”
Researchers at MIT and elsewhere have developed Boltz-2, an open-source generative AI model that can help researchers find new medicines faster, reports Alex Knapp for Forbes. The tool “can not only predict the structure of proteins, it can also predict its binding affinity–that is, how well a potential drug is able to interact with that protein,” explains Knapp. “This is crucial in the early stages of developing a new medicine.”
Graduate students Anika Jane Beamer, Nanticha Ocharoenchai, Pratik Pawar and Paulina Rowińska write for GBH to highlight health care deserts in the Boston area. “There are no hospitals or emergency care facilities in Mattapan,” they write. “With the closure of Carney Hospital, the nearest emergency room is at Brigham and Women’s Faulkner Hospital, over three miles away. Getting there can be difficult.”
Emily Young '18, co-founder and CEO of MIT D-Lab spinout Moving Health, speaks with The World’s Jeremy Siegel about her startup’s commitment to transforming “maternal healthcare in rural Ghana, where access to ambulances is severely limited, by creating an emergency transportation network that uses motorized ambulances." Young discovered that “what rural communities needed most was transportation that could actually handle rough terrain while still being cost effective and easy to scale at a local level.”
Prof. Canan Dagdeviren speaks with NBC Boston reporter Priscilla Casper about her work developing a wearable ultrasound scanner that can be used for early breast cancer detection, with the goal of empowering “women to monitor their own bodies, on their own time and in the comfort of their own home.” Dagdeviren explains that “our hope [is to] collect a lot of data and use AI to predict what will happen to breast tissue over time.”
The new Hood Pediatric Innovation Hub, a cornerstone of MIT’s Health and Life Sciences Collaborative (MIT HEALS), is aimed at addressing “underinvestment in pediatric healthcare innovations,” reports Isabel Hart for the Boston Business Journal. Prof. Elazer Edelman, faculty lead for the hub, explains that: “We are trying to build a new culture providing innovation to those who have least access to it and will most benefit from it.”
Prof. David Sontag, Monica Agrawal PhD '23, Luke Murray SM '22, and Divya Gopinath '19, MEng '20 co-founded Layer Health - an AI healthcare startup that is applying large language models (LLMs) to help clinicians with medical chart reviews and data abstraction, reports Seth Joseph for Forbes. “The same chart review problem we’re solving with our clinical registry module is faced by clinicians at the point of care,” says Sontag. “For example, one of our next modules will focus on real-time clinical decision support to help automate clinical care pathways, leading to more reliable, high-quality care."
Newsha Ghaeli PhD '17, co-founder of BioBot Analytics, speaks with GBH Morning Edition host Mark Herz about the company’s role in helping public health officials during the Covid-19 pandemic. “When we started the company, the vision was really that wastewater is a source of very important source on human health,” says Ghaeli.
Prof. Jon Gruber speaks with former Massachusetts Secretary of Public Safety and Security Andrea Cabral and GBH Boston Public Radio host Margery Eagan about the future of health care in the United States.
MIT researchers have developed a biosensor “the size of a stick of gum that can be implanted under the skin and deliver naloxone if vital signs indicate an overdose,” reports David Ovalle and Elana Gordon for The Washington Post.
A new commentary by Prof. Jonathan Gruber and his colleagues outlines a proposal for a new long-term care at home plan, aimed at enabling seniors to stay in their homes, reports Jonathan Cohn for HuffPost. “Relative to other countries, we’re very nursing home focused, and we’re not really doing enough to keep people at home,” says Gruber. “I also just think it’s a valuable benefit to people that makes their lives better.”
Profs. Canan Dagdeviren and Hugh Herr speak with CNN discuss their work aimed at empowering patients and doctors. Inspired by her aunt’s experience with breast cancer, Dagdeviren and her students are developing new wearable devices that could help detect cancer at an earlier stage. Says Herr of his work developing prosthetics that can be controlled by the human nervous system: “There will be a point where technology is so sophisticated that we can actually rebuild limbs after amputation that will be as good and, ultimately, they will be better than intact biological limbs.” Herr adds that in the future he hopes “the conversation will not be about human limitation anymore. It will be about human ability and human expression.”
Writing for Forbes, Senior Lecturer Guadalupe Hayes-Mota '08 MS '16, MBA '16 explores the challenges, opportunities and future of AI-driven drug development. “I see the opportunities for AI in drug development as vast and transformative,”
CNN visits the lab of Prof. Canan Dagdeviren to learn more about her work developing wearable ultrasound devices that could help screen for early-stage breast cancer, monitor kidney health, and detect other cancers deep within the body. “Wearable technology will grow rapidly in the near future,” says Dagdeviren. “But in the far future, they will be one of the most powerful tools that we will be seeing in our daily life.”