Genetics

CBS News spotlights how two MIT researchers have been named to key roles on the Biden administration’s science team. Prof. Eric Lander, president and founding director of the Broad Institute, has been nominated to lead the Office of Science and Technology Policy, and Maria Zuber, MIT’s vice president for research, will co-chair the President's Council of Advisors on Science and Technology. Zuber said she hopes to "restore trust in science, and pursue breakthroughs that benefit all people."

Prof. Eric Lander, president and founding director of the Broad Institute, and Maria Zuber, MIT’s vice president for research, have been nominated to leading roles on the Biden administration's science team, report Nidhi Subbaraman and Alexandra Witze for Nature. “These are excellent appointments, highly qualified and experienced, and well grounded in science,” says Rita Colwell, a professor at University of Maryland at College Park and former director of the National Science Foundation

AP reporter Seth Borenstein writes about how President-elect Joe Biden is nominating Prof. Eric Lander of the Broad Institute to serve as his chief science officer and lead the Office of Science and Technology Policy, and has selected Maria Zuber, vice president for research at MIT, to co-chair the President’s Council of Advisors on Science and Technology. Francis Collins, director of the NIH, called Lander, “brilliant, visionary, exceptionally creative and highly effective in aspiring others. I predict he will have a profound transformational effect on American science.”

New York Times reporter Carl Zimmer writes that Prof. Eric Lander, president and founding director of the Broad Institute, has been nominated to serve as director of the Office of Science and Technology Policy and to serve as a presidential science advisor. MIT Vice President for Research Maria Zuber will co-chair the President’s Council of Advisors on Science and Technology.

Prof. Eric Lander, president and founding director of the Broad Institute, has been nominated by President-elect Joe Biden to lead the Office of Science and Technology Policy, which Biden will make a Cabinet-level position, reports Sarah Kaplan for The Washington Post. Maria Zuber, MIT’s vice president for research, will co-chair the President’s Council of Advisors on Science and Technology.

STAT reporter Kate Sheridan spotlights the work of Kartik Ramamoorthi PhD ’14 and his gene therapy company Encoded. Sheridan explains that Encoded’s first gene therapy will “target Dravet syndrome — a rare condition that can cause seizures, cognitive deficits, and mobility problems.”

A new study by MIT researchers finds that there are differences in how genes are used in men and women, reports Angus Chen for WBUR. “I think we are at present missing a lot because we operate with what is essentially a unisex model in biomedical research,” explains Prof. David Page.

Reporting for WBUR, Carey Goldberg highlights how MIT researchers have developed a new RNA editing tool that could be used to tweak a gene that raises the risk of Alzheimer’s disease. As the effects of RNA editing are not permanent, “it's almost like a small, pill-like version of gene therapy,” explains research scientist and McGovern Fellow Omar Abudayyeh.

President Emerita Susan Hockfield discusses her new book, “The Age of Living Machines,” her work as a neuroscientist, and the future of science and technology during a curated lunch conversation with HUBweek and Boston.com. Hockfield explains that a revolution spurred by the convergence of biology with engineering will lead to new technologies built by biology.

In an excerpt from her new book published in The Wall Street Journal, President Emerita Susan Hockfield explores how the convergence between biology and engineering is driving the development of new tools to tackle pressing human problems. Hockfield writes that for these world-changing technologies to be realized requires “not only funding and institutional support but, more fundamentally, a commitment to collaboration among unlikely partners.”

President Emerita Susan Hockfield speaks with Jim Braude of WGBH’s Greater Boston about her book, “The Age of Living Machines.” “We are looking at a population of over 9.7 billion by 2050,” explains Hockfield. “We are not going to get there without war or epidemics or starvation if we don’t develop technologies that will allow us to provide energy, food, water, health and health care sustainably.”

Boston Globe reporters Ysabelle Kempe and Felice Freyer write that MIT is launching a new Down syndrome research center with a gift from the Alana Foundation. “I really want people with different conditions and different ability to feel they are not different, to feel that they belong, and to enhance their capability to interact and to enjoy life,” explains Prof. Li-Huei Tsai.

MIT is launching a new Down syndrome research center thanks to a gift from the Alana Foundation, reports the AP. The center “will combine the expertise of scientists and engineers in an effort to increase understanding of the biology and neuroscience of Down syndrome.”

New York Times reporter Heather Murphy highlights a new study co-authored by Prof. Peter Reddien that details the master gene responsible for enabling worms to regenerate. “Something has to decide in cells which notes to play; which genes to turn on,” explains Reddien. “There are some genes whose function it is to tell other genes whether to be on or off. This is one of those kinds of genes.”

TIME reporter Alice Park writes that in a Nature commentary, an international group of scientists has called for a temporary ban on studies using gene-editing on human embryos. “Our question is, how should nations make decisions about technologies like gene editing going forward?” says Prof. Eric Lander, director of the Broad Institute and one of the authors of the commentary.