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Genetic engineering

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BBC News

BBC News reporter Michelle Roberts writes that MIT researchers have fine-tuned the CRISPR-Cas9 genome editing system to make it safer and more accurate. This development is "vital if it [CRISPR] is to be used in humans to cure inherited diseases or inborn errors,” explains Roberts. 

Popular Science

Alexandra Ossola writes for Popular Science that MIT researchers have found a molecule that could make the CRISPR gene-editing technique more precise. The new molecule “makes the editing process easier to control and could create new possibilities for how scientists can edit DNA in the future.”

Boston Globe

Boston Globe reporter Sharon Begley writes that Prof. Feng Zhang has uncovered enzymes that could be used to edit genes more precisely than the proteins currently used by CRISPR. Begley explains that the discovery means that CRISPR could become an “even more powerful tool to reveal the genetic defects underlying diseases and to perhaps repair them.”

Wired

In an article for Wired, Sarah Zhang writes that MIT researchers have identified a new gene-editing system that could prove more effective than current techniques. The new system involves, “a different protein that also edits human DNA, and, in some cases, it may work even better than Cas9,” the protein used for DNA editing.

WBUR

Professor Kenneth Oye speaks with WBUR’s Sacha Pfeiffer about his recent research that details a new way to alter the genomes of organisms and the need for a public discussion about the potential implications and benefits of this new technology. 

Financial Times

Three scientific papers about the Y chromosome, which determines maleness in humans and most other mammals, should lay to rest the myth that it may disappear after a few more million years of evolution,” Financial Times reporter Clive Cookson writes of MIT research on the Y chromosome.

Nature

Professor Ron Weiss contributes to this article in Nature on how to overcome the greatest obstacles in the field of synthetic biology. Weiss recommends improving the efficiency of the design of genetic parts.