Science reporter Tania Rabesandratana examines how MIT researchers are gathering and identifying gut bacteria from people around the world. The effort is aimed at preserving the human gut’s microbial biodiversity and developing new treatments for diseases. “I'm 100% confident that there are relevant medical applications for hundreds of strains we've screened and characterized,” explains Prof. Eric Alm.
Wired reporter Megan Molteni highlights Prof. Aviv Regev’s work leading the Human Cell Atlas, an effort to catalog the cells in the human body that could eventually serve as a roadmap for understanding and treating disease. “From the beginning we have designed this as a public good and an open resource to enable science around the world,” Regev explains.
Writing for STAT, Eric Boodman highlights how Prof. Jing-Ke Weng’s lab at the Whitehead Institute has mapped the genome of a firefly in an effort to understand how fireflies acquired the ability to glow. The researchers hope their findings will eventually be used to develop “better laboratory tools for studying disease and developing treatments.”
Local biotech companies raised money to help MIT’s Bear Lab study Fragile X syndrome by competing in lawn games, writes Allison Hagan for The Boston Globe. The $30,000 raised provides “a very real chance at a success in this disease, and it’s going to have a much broader impact,” says Prof. Mark Bear.
Boston Herald reporter Alexi Cohan highlights a new lab at MIT, led by Prof. Tyler Jacks, that will investigate how the immune system can be used to treat and manage pancreatic cancer. “In the long term we hope that the work that we are doing will help us diagnose the disease at even early stage and maybe even prevent it altogether,” Jacks explains.
MIT researchers have identified how blood cells clump together in patients with sickle-cell disease, writes Shi Yinglun for the Xinhua News Agency. Yinglun explains that the findings represent "a step toward being able to predict when these events known as vaso-occlusive pain crises might occur.”
In an article for The New York Times about how scientists are developing new ways to treat disease using bacteria, Carl Zimmer highlights how MIT startup Synlogic is developing what could be the first FDA-approved synthetic biology-based medical treatment for a disease called phenylketonuria.
STAT reporter Orly Nadell Farber writes about a new study by MIT researchers that shows glaucoma might be caused by T-cells, an integral component of the human body’s immune system, attacking retinal cells. Farber explains that, “this discovery could unlock a critical new door for treatment options.”
A new study by MIT researchers provides evidence that glaucoma may be caused by an autoimmune disease, according to a HealthDay News piece published by UPI. “Further research will try to determine whether other parts of the immune system play a role in glaucoma, and whether autoimmunity is a factor in degenerative brain diseases.”
MIT researchers have discovered that probiotics can prevent cholera and treat early stage cases of the disease, reports Laney Ruckstuhl for The Boston Globe. The findings, led by Prof. James Collins, “could have implications for other diseases as well because scientists were previously unaware that bacterial infections could be vulnerable to naturally occurring probiotics,” notes Ruckstuhl.
Yahoo! reporter Elise Solé highlights how Alejandra Falla successfully completed her PhD studies at MIT while pregnant with her daughter, Clara. Clara sported a miniature MIT regalia to Commencement. “It started as a joke but we decided that Clara had earned her Ph.D. in the womb,” says Falla. “She deserved to graduate with me.”
Researchers from a number of universities, including MIT, have developed a new refillable, implantable device that can deliver drugs to the heart tissue to help treat a heart attack, reports Xinhua. "After a heart attack we could use this device to deliver therapy to prevent a patient from getting heart failure," explains Prof. Ellen Roche.
Boston Herald reporter Lindsay Kalter writes that MIT researchers have developed a wireless ingestible sensor that could one day be used to diagnose and treat disease. “The most exciting thing is that we can wirelessly control tiny implants even though they have no batteries at all,” says Prof. Fadel Adib.
Researchers at MIT have developed a device “that can receive power and communicate wirelessly from inside the body,” which could eventually be used for drug delivery, to treat disease or to monitor overall health, reports Allen Cone for UPI. "Having the capacity to communicate with these systems without the need for a battery would be a significant advance," said research affiliate Gio Traverso.
A new study led by Prof. Li-Huei Tsai reveals more information about the possible link between Alzheimer’s disease and the gene variant APOE4, writes Martin Finucane for The Boston Globe. The researchers discovered that by editing the gene into the more common APOE3 variant, “they could eliminate the signs of Alzheimer’s in brain cells,” said Finucane.