Diagnostics

Writing for Scientific American, Carolyn Barber spotlights how researchers from MIT are developing cheap, fast and easy to use diagnostics for Covid-19 that can deliver results in minutes. “They are called lateral flow assays, but manifestly they are paper-strip tests that have an antibody embedded on filter paper,” writes Barber. “If a saliva sample has coronavirus present, the antibody will bind that viral antigen, turning the test positive, much like a pregnancy test works.”

WHDH spotlights MIT startup E25Bio, which is developing a new rapid test to diagnose Covid-19. The test being developed by E25Bio is a paper strip that can deliver test results in 15 minutes, WHDH explains.

Prof. James Collins speaks with Molly Wood of Marketplace about his work developing a faster, cheaper and more accurate Covid-19 diagnostic. Collins explains that his research group is “using synthetic biology to create highly sensitive, low-cost diagnostics, some that are now approved for use in clinical diagnostics labs, and now we’re moving towards point-of-care diagnostics, as well as at-home diagnostics.”

Reporting for USA Today, Karen Weintraub spotlights how researchers from MIT and 3M are collaborating on a rapid, low-cost diagnostic test for Covid-19. "The world needs as many useful tests as possible as fast as possible," says Prof. Hadley Sikes.

Prof. Sangeeta Bhatia and senior postdoctoral associate Leslie Chan discuss their work developing a synthetic biosensor to diagnose lung disease. Chan explains that “instead of relying on naturally occurring breath volatiles, we wanted to be able to engineer the breath signal that we could use to monitor lung disease.”

CNBC reporter Will Feur spotlights how researchers from MIT are working with 3M on developing a rapid coronavirus antigen test. The test “will be a paper-based point-of-care testing device, which will help reduce the cost,” Feur explains.

Researchers from MIT and 3M are developing a new rapid antigen test for Covid-19, reports Carl O’Donnell for Reuters. “The test would produce results within minutes and could be administered on a low-cost, paper-based device, similar to a home pregnancy test, that could be delivered at the point of care,” writes O’Donnell.

TechCrunch reporter Darrell Etherington writes that researchers from MIT and 3M are working on creating a new diagnostic tool for Covid-19 that can be manufactured cheaply and in large volumes for mass distribution. “The goal is to create a test that detects viral antigens,” Etherington explains, adding that the tests “provide results much faster than the molecular PCR-based test.”

Amy Dockser Marcus of The Wall Street Journal writes about the growing interest in using CRISPR as a diagnostic tool, which led to a collaboration between MIT Professors James Collins and Feng Zhang. The result is Sherlock, a diagnostic platform that can identify viruses “based on extremely low amounts of RNA in blood and urine samples,” explains Dockser Marcus.

FOX 25’s Bob Dumas reports on a study by MIT Medical that shows most parents could successfully perform strep tests at home. David Diamond, associate medical director of MIT Medical, explains that in the healthcare field, “we are empowering patients to help us take care of their health,” adding that this test, “would be yet another advance in this regard.”

Reporting for WBUR, Karen Weintraub speaks with Profs. Angela Belcher, Sangeeta Bhatia and Paula Hammond about their work developing tiny tools to target cancer cells. Bhatia explains that their collaboration feels like, “a dream team of people that are interested in nanoscience and nanotechnology and focusing those advances on cancer.”

In a piece for Slate about using smart phone to diagnose medical conditions, Aimee Swartz writes about work by MIT Media Lab Fellow Max Little on algorithms that could help smart phones diagnose Parkinson’s disease. The algorithm “will detect specific variations in voice quality, such as tremors, breathlessness, and vocal weakness,” writes Swartz.

Jeremy Hobson interviews Prof. Sangeeta Bhatia about her work 3-D printing tiny human livers on NPR’s Here and Now. The livers are, “about the size of the pin of a needle, and they allow us to do drug testing to test if drugs would be safe when they got into humans,” Bhatia explains. 

The Boston Globe profiles Dr. Sangeeta Bhatia and the new low-cost urine test she developed to detect cancer, as well as her work applying engineering techniques to medicine.

Researchers at MIT have developed a new method to diagnosis cancer, writes Liat Clark in Wired. The new technique, which identifies proteins in urine associated with cancer, works like a pregnancy test and could be used to improve cancer care in developing nations, Clark reports.