Diagnostic devices

Amy Dockser Marcus of The Wall Street Journal writes about the growing interest in using CRISPR as a diagnostic tool, which led to a collaboration between MIT Professors James Collins and Feng Zhang. The result is Sherlock, a diagnostic platform that can identify viruses “based on extremely low amounts of RNA in blood and urine samples,” explains Dockser Marcus.

In an article for The Huffington Post, Susan Blumenthal highlights how researchers from MIT have developed a paper-based test for diagnosing the Zika virus. Blumenthal writes that “the test consists of a paper covered with yellow dots that turns purple in the presence of the RNA of the virus.”

Lindsay Kalter reports for The Boston Herald that researchers from MIT, Philips, and Boston Medical Center are developing a non-invasive way to diagnose head injuries. Kalter explains that the study is part of a new collaboration between MIT and Philips and will “use data from an ultrasound machine taking measurements of blood pressure and flow.”

Researchers from MIT, Philips and Boston Medical Center are collaborating on new technology to diagnose brain injuries, reports Nidhi Subbaraman for BetaBoston. “The goal is to investigate whether ultrasound readers can help doctors assess the severity of a head injury,” Subbaraman writes. 

Boston Magazine reporter Jamie Ducharme writes that MIT researchers have developed a new digitized pen that could be used to improve a test that screens for Alzheimer’s and other cognitive impairments. “What the pen does is capture the writing with considerable temporal and spatial accuracy,” Prof. Randall Davis explains. 

MIT researchers have developed a new tool that could be used to predict dementia earlier than is currently possible and with greater accuracy, reports Liat Clark for Wired. The researchers hope the new technique could be used to cut down on the number of “hours spent diagnosing, or potentially misdiagnosing, a disorder.”

Alexandra Ossola writes for Popular Science about a computer program created by MIT researchers that can aid in early detection of dementia by analyzing a patient’s drawings. The program “may enable doctors to diagnose patients much more quickly, and to intervene earlier to stave off the onset of cognitive degeneration.”

In a piece for Slate about using smart phone to diagnose medical conditions, Aimee Swartz writes about work by MIT Media Lab Fellow Max Little on algorithms that could help smart phones diagnose Parkinson’s disease. The algorithm “will detect specific variations in voice quality, such as tremors, breathlessness, and vocal weakness,” writes Swartz.

WBUR reporter Carey Goldberg highlights a new technique developed by MIT researchers, “just out in the Proceedings of the National Academy of Sciences that describes success in diagnosing cancer with a simple, paper-based test — an advance that could be particularly important for the developing countries where 70 percent of cancer deaths now occur.”