For stem cells, bigger doesn’t mean better
MIT biologists show that enlargement of blood stem cells restricts their ability to generate new blood cells during aging.
Hunting a “Jekyll-and-Hyde” molecule
A screening method developed by MIT researchers targets hydrogen peroxide in the search for new cancer therapeutics.
Solid, liquid, or gas? Technique quickly identifies physical state of tissues and tumors
The method could be a route to quicker, less invasive cancer diagnoses.
Cellular environments shape molecular architecture
Researchers glean a more complete picture of a structure called the nuclear pore complex by studying it directly inside cells.
Katie Galloway receives NIH award to develop foundational tools for cellular engineering
Using a combination of stem cell biology, systems biology, synthetic biology, and chromatin engineering, the Galloway lab will define the molecular regulatory rules of cell-fate transitions.
Accelerating the pace of engineered cell therapies, from lab to bedside
Kytopen is speeding up both discovery and delivery of engineered cell therapies with its transformative Flowfect platforms.
Biologists discover a trigger for cell extrusion
Study suggests this process for eliminating unneeded cells may also protect against cancer.
SMART researchers develop 15-minute immune-profiling assay
Deterministic lateral displacement assay can rapidly assess host inflammatory response, identifying a potentially life-threatening hyper-aggressive immune response.
Membrane around tumors may be key to preventing metastasis
Tough as plastic wrap but elastic like a balloon, the lining could be a target for therapies to limit cancer cells from spreading.
Study reveals how egg cells get so big
Oocyte growth relies on physical phenomena that drive smaller cells to dump their contents into a larger cell.
Basic cell health systems wear down in Huntington’s disease, analysis shows
A new computational approach for analyzing complex datasets shows that as disease progresses, neurons and astrocytes lose the ability to maintain homeostasis.
Metabolic mutations help bacteria resist drug treatment
Study suggests forcing bacteria to burn more energy could make them more susceptible to antibiotics.
3 Questions: Lindsay Case on how cells organize and sense the world
Case’s new lab investigates why cancer arises when disruptions in cellular organization change how cells sense mechanical forces.
Catching cancer in the act
Using CRISPR technology, researchers are tracking the lineage of individual cancer cells as they proliferate and metastasize in real-time.
Why cancer cells waste so much energy
MIT study sheds light on the longstanding question of why cancer cells get their energy from fermentation.