Broad Institute

AP reporter Seth Borenstein writes about how President-elect Joe Biden is nominating Prof. Eric Lander of the Broad Institute to serve as his chief science officer and lead the Office of Science and Technology Policy, and has selected Maria Zuber, vice president for research at MIT, to co-chair the President’s Council of Advisors on Science and Technology. Francis Collins, director of the NIH, called Lander, “brilliant, visionary, exceptionally creative and highly effective in aspiring others. I predict he will have a profound transformational effect on American science.”

New York Times reporter Carl Zimmer writes that Prof. Eric Lander, president and founding director of the Broad Institute, has been nominated to serve as director of the Office of Science and Technology Policy and to serve as a presidential science advisor. MIT Vice President for Research Maria Zuber will co-chair the President’s Council of Advisors on Science and Technology.

Prof. Eric Lander, president and founding director of the Broad Institute, has been nominated by President-elect Joe Biden to lead the Office of Science and Technology Policy, which Biden will make a Cabinet-level position, reports Sarah Kaplan for The Washington Post. Maria Zuber, MIT’s vice president for research, will co-chair the President’s Council of Advisors on Science and Technology.

Research affiliate Fei Chen and his colleagues have developed a new method that could be used to uncover the organization and sequence of DNA inside intact cells, reports Nature. The new method could be used to “help to reveal how genome organization changes with disease.”

Professor Angelika Amon, an award-winning cell biologist and “an advocate for the kinds of studies that grind away outside of the limelight,” died on Oct. 29, reports Bryan Marquard for The Boston Globe. Amon’s daughter, Clara Weis, noted that Amon “was pretty much the best role model there is. She was very caring and understanding. She always knew what was happening and how to deal with it the right way.”

Prof. James Collins speaks with Boston 25 reporter Julianne Lima about the growing issue of antibiotic resistant bacteria and his work using AI to identify new antibiotics. Collins explains that a new platform he developed with Prof. Regina Barzilay uncovered “a host of new antibiotics including one that we call halicin that has remarkable activity against multi drug-resistant pathogens.”

Writing for The Boston Globe, Prof. Eric Lander, president and founding director of the Broad Institute, argues that the U.S. needs to take steps to ensure that "science benefits society and society trusts science…In the 2020s, the decision-making must include a much wider range of people, who will need to be prepared to grapple thoughtfully with hard choices.”

AP reporter Mark Pratt writes that the Broad Institute and Brigham and Women’s Hospital are launching a “six-month study of 10,000 people to help them better understand the prevalence of COVID-19 in the area and to help identify potential surges during the fall and winter.

The Broad Institute and Brigham and Women’s are launching a large-scale research study aimed at testing people for Covid-19 at home, reports Travis Anderson and Emily Sweeney for The Boston Globe. The initiative will “provide information on the prevalence of the virus in the area and could offer an early warning sign of a surge of new cases in the fall and winter,” Sweeney and Anderson explain.

WBUR’s Carey Goldberg chronicles how the Broad Institute of MIT and Harvard is processing over 70,000 Covid-19 tests a day for Massachusetts nursing homes, hot spots and over 100 colleges. Goldberg notes that the Broad’s testing capacity, “is now allowing thousands of college students to be on campus across the region.”

A CRISPR-based diagnostic test for Covid-19 developed by researchers from MIT and the Broad Institute could produce results within an hour, reports Deborah Becker for WBUR. "Using these technologies will really allow for much more rapid testing — down from days to sometimes less than an hour," said McGovern fellow Jonathan Gootenberg. "That would enable a drastic change in how the tracing and handling of the pandemic is done."

Prof. Sinan Aral speaks with GBH’s Arun Rath about his study showing that a lack of coordination between states on their reopening plans can lead to an influx in Covid-19 cases. Rath also spotlights the Broad Institute’s work processing over 1.5 million diagnostic tests for coronavirus since March 25.

On Sunday, August 30^th, the Broad Institute of MIT and Harvard performed its one-millionth test for Covid-19, reports Jonathan Saltzman for The Boston Globe. “Six months after the nonprofit institute in Cambridge began testing for the coronavirus to help overwhelmed laboratories and hospitals, the Broad reached the landmark as technicians, many of them recently hired, work around the clock,” writes Saltzman.

WBUR’s Carey Goldberg explores how MIT researchers developed a new CRISPR-based research tool that can be used to detect Covid-19. "A lot of things that we try fail," says research scientist Jonathan Gootenberg. "And that’s OK. Because sometimes you find these things that are really, really awesome."

Reporting for WBUR, Carey Goldberg highlights how MIT researchers have developed a new RNA editing tool that could be used to tweak a gene that raises the risk of Alzheimer’s disease. As the effects of RNA editing are not permanent, “it's almost like a small, pill-like version of gene therapy,” explains research scientist and McGovern Fellow Omar Abudayyeh.