Juan Enriquez writes for Wired that the intersection of Vassar and Main Streets is one of the most innovative areas in the world, highlighting how MIT plays a leading role in sparking innovation. Enriquez writes that this area “may generate one per cent to two per cent of the future global economy.”
The Broad Institute Foundry, a synthetic biology lab, has been awarded a new grant from DARPA to pursue research on engineering cells in an effort to “find better treatments for disease, make new biofuels, or create fabrics woven with life,” reports Alexandra Ossola for Popular Science.
Alexandra Ossola writes for Popular Science that MIT researchers have found a molecule that could make the CRISPR gene-editing technique more precise. The new molecule “makes the editing process easier to control and could create new possibilities for how scientists can edit DNA in the future.”
Boston Globe reporter Sharon Begley writes that Prof. Feng Zhang has uncovered enzymes that could be used to edit genes more precisely than the proteins currently used by CRISPR. Begley explains that the discovery means that CRISPR could become an “even more powerful tool to reveal the genetic defects underlying diseases and to perhaps repair them.”
In an article for Wired, Sarah Zhang writes that MIT researchers have identified a new gene-editing system that could prove more effective than current techniques. The new system involves, “a different protein that also edits human DNA, and, in some cases, it may work even better than Cas9,” the protein used for DNA editing.
Lloyd Mallinson reports for Boston.com that researchers from MIT and Harvard have discovered the link between obesity and genetics. “The uncovered cellular circuits may allow us to dial a metabolic master switch for both risk and non-risk individuals, as a means to counter environmental, lifestyle, or genetic contributors to obesity,” explains Prof. Manolis Kellis.
Prof. Manolis Kellis speaks with BBC reporter Andrew Peach about the discovery of a genetic “master switch” inside fat cells. This switch “decides whether every time we have a meal the excess calories will be stored as fat or whether they will actually be burned away as heat,” explains Kellis.
Prof. Manolis Kellis and his colleagues have discovered a metabolic switch linked to obesity, reports Chukwuma Muanya for The Guardian. “Obesity has traditionally been seen as the result of an imbalance between the amount of food we eat and how much we exercise, but this view ignores the contribution of genetics to each individual’s metabolism,” explains Kellis.
“Researchers at MIT and Harvard Medical School have analysed the genetics behind obesity,” writes Natasha Hinde for The Huffington Post. “They discovered a new pathway that controls human metabolism by prompting fat cells to store fat or burn it away.”
Andy Coghlan reports for New Scientist that MIT researchers have found a gene that determines whether fat cells store or burn energy. “You could say we’ve found fat cells’ radiator, and how to turn it up or down,” says Prof. Manolis Kellis.
Alice Park reports for TIME that researchers from MIT and Harvard have identified a pathway that controls how much fat cells burn or store. “What these results say is that we can reprogram all the major fat stores in humans by intervening in this particular pathway,” explains Prof. Manolis Kellis.
Researchers from MIT and Harvard have discovered how the key gene linked to obesity makes people fat, reports the Associated Press. The study revealed that “a faulty version of the gene causes energy from food to be stored as fat rather than burned.”
The Broad Institute is teaming up with Google to “create a simpler way to help far-flung scientists pursue their own research online,” reports Robert Weisman for BetaBoston. “Our mission is to empower the biomedical revolution that’s happening around the world,” explains Prof. Eric Lander, founding director of the Broad Institute.
In a piece for The Huffington Post, Zeynep Ilyaz explains how Prof. Sangeeta Bhatia serves as an inspiration to her, citing her research advances in biotech and medicine, and her mentorship of women pursuing careers in STEM fields. “Dr. Bhatia is constantly looking for the next groundbreaking discovery in health, which makes her an excellent role model for girls and women,” Ilyaz writes.
Alexandra Sifferlin of TIME reports that researchers from the Broad Institute have uncovered a new way to detect risk of blood cancer. The researchers found that “certain mutations that are not present at birth but instead develop as a person ages—called somatic mutations—may be indicators for later blood cancers,” Sifferlin explains.