Ian Sample of The Guardian writes that the Human Cell Atlas project, which will be co-led by the Broad Institute, aims to map the cells in the human body . “This will have a substantial impact on our scientific understanding and as a result, on our ability to diagnose, monitor and treat disease,” says Prof. Aviv Regev.
Researchers from the Broad Institute will co-lead an initiative aimed at mapping and describing every cell in the human body, writes Kate Kelland of Reuters. "We now have the tools to understand what we are composed of, which allows us to learn how our bodies work, and uncover how all these elements malfunction in disease," explains Prof. Aviv Regev.
A new study co-authored by researchers at the Broad Institute examines how exposure to microbes during childhood can impact the development of immune systems, reports Elissa Strauss for Slate. The researchers found that “while our individual habits are a factor in autoimmune disorders, they’re hardly the only cause.”
MIT researchers have discovered that a bacterium found in the human mouth can be used to form a new CRISPR gene-editing system that can target RNA, reports Carl Zimmer for The New York Times. The development “may open up a new front in gene engineering, gaining the ability to precisely adjust the proteins in cells, for instance, or to target cancer cells."
New Scientist reporter Colin Barras writes that MIT researchers have found they can program C2c2, an enzyme found in bacteria, to serve as an RNA-editing tool. Barras writes that the tool “promises to transform our understanding of RNA’s role in our growth and development, and provide a new avenue for treating infectious diseases and cancer.”
Melinda Moyer of Scientific American reports that researchers have found that people who used acid blockers to treat heart burn are at increased risk for developing intestinal infections. Moyer explains that the blockers “may limit the gut's diversity by reducing its acidity and thus creating an environment that is more or less amenable to certain microbes.”
Prof. Feng Zhang has been named a recipient of the 2016 Canada Gairdner International Award for his work on the development of the CRISPR gene-editing system, reports CBC News. CRISPR "may prove to be a ‘powerful therapeutic’ for treating human diseases by editing out harmful genetic mutations.”
Globe and Mail reporter Ivan Semeniuk spotlights Prof. Feng Zhang and his role in developing the CRISPR-Cas9 gene-editing system, for which he was honored as a recipient of the 2016 Canada Gairdner International award. “CRISPR genome editing technology is a really powerful platform,” says Zhang. “It think it will advance both our ability to understand disease and to develop treatments.”
Broad Institute researchers have been developing a treatment for schizophrenia, writes Haroon Siddique for The Guardian. “Understanding schizophrenia will similarly accelerate progress against this devastating disease that strikes young people,” says Broad Dir. Eric Lander.
Scientists at the Broad Institute of MIT and Harvard have “identified key genetic traits that for the first time point to a biological mechanism behind schizophrenia,” writes Shirley Wang of The Wall Street Journal.
In an article for The Boston Globe’s special section about the 2015 Bostonians of the Year, Sharon Begley writes about the work of Prof. Feng Zhang. Begley writes that Zhang, "is one of the world’s most creative and influential biological engineers, able to see possibilities where others don’t.”
BBC News reporter Michelle Roberts writes that MIT researchers have fine-tuned the CRISPR-Cas9 genome editing system to make it safer and more accurate. This development is "vital if it [CRISPR] is to be used in humans to cure inherited diseases or inborn errors,” explains Roberts.
In an article for The New Yorker, Michael Specter writes about Prof. Feng Zhang and his work with CRISPR. Specter writes that Zhang was first inspired to pursue a career in science when he attended Saturday morning molecular biology classes as a middle school student. Zhang recalls that the class, “really opened my imagination.”
STAT reporter Sharon Begley profiles Prof. Feng Zhang. Begley writes that Zhang’s “discoveries could finally bring cures for some of the greatest causes of human suffering, from autism and schizophrenia to cancer and blindness.”
Juan Enriquez writes for Wired that the intersection of Vassar and Main Streets is one of the most innovative areas in the world, highlighting how MIT plays a leading role in sparking innovation. Enriquez writes that this area “may generate one per cent to two per cent of the future global economy.”