Washington Post reporter Matt Schudel writes about the impact Prof. Emerita Suzanne Corkin’s work had on our understanding of memory and cognitive disorders. Schudel writes that Corkin, who died on June 4, “made significant contributions to the study of Alzheimer’s disease and Parkinson’s disease, and helped identify regions of the brain affected by degenerative disorders.”
MIT researchers have discovered that a bacterium found in the human mouth can be used to form a new CRISPR gene-editing system that can target RNA, reports Carl Zimmer for The New York Times. The development “may open up a new front in gene engineering, gaining the ability to precisely adjust the proteins in cells, for instance, or to target cancer cells."
New Scientist reporter Colin Barras writes that MIT researchers have found they can program C2c2, an enzyme found in bacteria, to serve as an RNA-editing tool. Barras writes that the tool “promises to transform our understanding of RNA’s role in our growth and development, and provide a new avenue for treating infectious diseases and cancer.”
Prof. Emerita Suzanne Corkin, whose work with a famous amnesia patient was instrumental in uncovering the nature of memory, died on May 24, reports Benedict Carey for The New York Times. Carey writes that Corkin’s work “helped settle a debate about the function of the hippocampus in retrieving and reliving past experiences.”
Prof. Earl Miller speaks with Meghna Chakrabarti, host of Radio Boston, about the dangers of distracted driving. Miller explains that our brains “have a very limited capacity for simultaneous thought.” He adds that people have a hard time ignoring their phones while driving because the “brain evolved to find new information rewarding.”
Helen Shen writes for Nature that MIT researchers have developed a technique for assembling and operating an automated system for “whole-cell patch-clamping”, a method of monitoring the activity of brain cells. “Our hope is that we can help as many people as possible to answer questions about how neurons compute,” explains Prof. Edward Boyden.
Prof. Feng Zhang has been named a recipient of the 2016 Canada Gairdner International Award for his work on the development of the CRISPR gene-editing system, reports CBC News. CRISPR "may prove to be a ‘powerful therapeutic’ for treating human diseases by editing out harmful genetic mutations.”
Globe and Mail reporter Ivan Semeniuk spotlights Prof. Feng Zhang and his role in developing the CRISPR-Cas9 gene-editing system, for which he was honored as a recipient of the 2016 Canada Gairdner International award. “CRISPR genome editing technology is a really powerful platform,” says Zhang. “It think it will advance both our ability to understand disease and to develop treatments.”
MIT researchers have found a possible link between attention deficit disorders and autism, reports Lindsay Kalter for The Boston Herald. “One of the long-term goals is gene therapy where we can actually introduce genetic material that might be missing from the human,” explains grad. student Michael Wells.
Popular Science reporter Claire Maldarelli writes that researchers from MIT have identified how sensory overload occurs for people with neurodevelopmental disorders. Based off their findings, the researchers hope they can "classify these disorders in a better way, but also develop therapies that alleviate or diminish the symptoms.”
MIT researchers have shown that memories can be restored using optogenetics, findings that could help treat Alzheimer’s. According to The Economist, the findings provide evidence “about how memories are lost during the early stages of the disease and may point to how…those memories might be brought back.”
A new study conducted by MIT researchers suggests that optogenetics could one day be used to help stimulate lost memories in Alzheimer’s patients, reports Ashley Welch for CBS News. Walsh writes that the researchers have “found evidence that ‘lost’ memories may just be inaccessible, with the potential to be retrieved.”
In an article posted by Scientific American, Sara Reardon writes that MIT researchers have shown that patients with Alzheimer’s can still form new memories and that lost memories could potentially be recalled using optogenetics. The findings “may allow more targeted stimulation, especially once researchers understand what happens to memories after they leave the hippocampus.”
Huffington Post reporter Ann Brenoff writes about a new MIT study that finds that Alzheimer’s patients may one day be able to recover lost memories using optogenetics. “The findings raise the hope — and possibility — that future treatments might indeed reverse some of the memory loss in early-stage Alzheimer’s patients.”
Washington Post reporter Ariana Eunjung Cha writes that MIT researchers have found evidence that memories lost due to Alzheimer’s disease could potentially be recalled using optogenetics. Cha writes that the research “raises the hope of future treatments that could reverse some of the ravages of the disease on memory.”