Biological engineering

Satellite Bio, a startup co-founded by Prof. Sangeeta Bhatia, aims to create “tissue implants to ‘repair, restore, or even replace’ diseased or dying organs,” reports Ryan Cross for The Boston Globe.

MIT announced five projects "targeting the world's toughest climate riddles" that were selected following a rigorous two-year competition, reports Benjamin Kail for Boston Business Journal. “Climate Grand Challenges represents a whole-of-MIT drive to develop game-changing advances to confront the escalating climate crisis, in time to make a difference,” says President L. Rafael Reif.

Prof. Peter Dedon discusses his research investigating how scientists can make new antibiotics by inserting “engineered genes into spots along the bacterial genome that optimize protein production,” writes Carrie Arnold for Scientific American. “There’s great potential there,” Dedon says. “There’s a whole new world of antibiotic targets.”

Newsha Ghaeli ’17 - president and co-founder of Biobot, a public health research, data and analytics firms that has developed and promoted wastewater surveillance technology - speaks with Vox reporter Muizz Akhtar about how wastewater surveillance can be used to predict and prepare for future pandemics. “Our vision is that this is a permanent infrastructure layer on our sewer systems, so that it becomes one of the core kinds of pandemic preparedness in this country and disease surveillance globally,” says Ghaeli.

Professor Linda Griffith speaks with Radio Boston host Tiziana Dearing about her research on endometriosis. The dream is “that we get diagnosis at the start, and you get your therapy at the start, and you don’t even develop the disease,” says Griffith.

STAT has named Noubar Afeyan ’87, Cornelia Bargmann PhD ’87, Prof. Regina Barzilay and Prof. Sangeeta N. Bhatia to their list of trailblazing researchers working in the life sciences. “Many of the STATUS List are well-known as change makers; others are largely unheralded heroes. But all have compelling stories to tell,” writes STAT.

Boston Globe reporter Pranshu Verma spotlights MIT startup Biobot Analytics, co-founded by Mariana Matus ’18 and Newsha Ghaeli ’17, for their work studying sewage data to better predict the spread of Covid-19 in communities. “For health officials, it [the data] confirms whether Covid spikes in the community are real, and not due to increased testing or other factors,” writes Verma. “Moreover, Covid levels in waste water are a leading indicator for new clinical cases, giving health officials a few days’ notice if they’ll see more sick patients showing symptoms.”

STAT reporters Katie Palmer and Casey Ross spotlight how Prof. Regina Barzilay has developed an AI tool called Mirai that can identify early signs of breast cancer from mammograms. “Mirai’s predictions were rolled into a screening tool called Tempo, which resulted in earlier detection compared to a standard annual screening,” writes Palmer and Ross.

MIT researchers are developing innovations aimed at improving Covid-19 diagnostics, including an atomic-level test designed to increase testing accuracy, reports Steven Zeitchik for The Washington Post. Professor James Collins and his team are developing “a mask that uses freeze-dried technology to detect the coronavirus.”

Prof. Regina Barzilay speaks with Good Morning America about her work developing a new AI tool that could “revolutionize early breast cancer detection” by identifying patients at high risk of developing the disease. “If this technology is used in a uniform way,” says Barzilay, “we can identify early who are high-risk patients and intervene.”

Washington Post reporter Steve Zeitchik spotlights Prof. Regina Barzilay and graduate student Adam Yala’s work developing a new AI system, called Mirai, that could transform how breast cancer is diagnosed, “an innovation that could seriously disrupt how we think about the disease.” Zeitchik writes: “Mirai could transform how mammograms are used, open up a whole new world of testing and prevention, allow patients to avoid aggressive treatments and even save the lives of countless people who get breast cancer.”

Prof. Timothy Lu, Prof. Jim Collins and Philip Lee ’03 co-founded Senti Bio, a biotechnology company that uses gene circuit technology to create cell and gene therapies that can sense and respond to ailments inside the body, reports Sohini Podder for Reuters. “The way I like to think about it – just like you can program a computer with different programs or different maps, we can do the same thing with medicines,” says Lu.

MIT scientists have discovered a way to watch and record the development of butterfly scales from the inside of a butterfly’s chrysalis, reports Elizabeth Gamillo for Smithsonian Magazine. “The team plans on further exploring the structure of butterfly wings and the reasoning behind the ridged design,” writes Gamillo.

Marcos Berríos ‘06, Christina Birch PhD ’15, and Christopher Williams PhD ’12 are among the ten selected to be a part of NASA’s 2021 astronaut candidate class, reports Emre Kelly for USA Today. “Flanked by T-38 Talon jets to be used over their two-year training course at Johnson Space Center in Houston, NASA officials introduces the 2021 class of six men and four women in front of their families, friends, and soon-to-be colleagues,” writes Kelly.  

Marcos Berríos ‘06, Christina Birch PhD ‘15 and Christopher Williams PhD ’12 have been selected as part of NASA’s 2021 astronaut candidate class, reports WBUR’s Bill Chappell. “Alone, each candidate has ‘the right stuff,’ but together they represent the creed of our country: E pluribus unum – out of many, one,” said NASA Administrator Bill Nelson.