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Biological engineering

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BBC News

Professor Robert Langer has won the Queen Elizabeth Prize for Engineering for his pioneering work with medical technologies, reports David Shukman for BBC News. Shukman notes that “as many as two billion people have in some way been touched by technologies devised and developed by him and his teams.”

Financial Times

Prof. Robert Langer has been awarded the Queen Elizabeth Prize for Engineering, writes Financial Times reporter Clive Cookson. Lord Broers, chair of the QE Prize judges, explains that Langer was honored for his “immense contribution to healthcare and to numerous other fields.”

Scientific American

Karen Hopkin of Scientific American writes about a new method developed by MIT researchers for increasing the size of tissue samples to allow for better observation. Thus far, the researchers have used the new technique to “peer into the brains of mice, fruit flies and zebrafish,” Hopkin explains. 

New Scientist

Using a polymer found in diapers that swells on contact with water, Prof. Ed Boyden and his colleagues have developed a method for enlarging tissue samples to allow for better 3-D imaging, writes Jessica Hamzelou for New Scientist. The team can enlarge samples to more than four times their original size, Hamzelou reports.

New York Times

John Markoff writes for The New York Times about a new technique for observing minuscule features in biological samples developed by Prof. Ed Boyden and his colleagues. The researchers “were able to increase the physical size of cultured cells and tissue by as much as five times while still preserving their structure,” Markoff explains. 

PBS NewsHour

Rebecca Jacobson of the PBS NewsHour reports that MIT researchers have developed a new technique to enlarge tissue samples, allowing scientists to create high-resolution images of specimens. Prof. Ed Boyden explains that “now you can see tiny structures with your own eyes.” 

Boston Globe

Carolyn Johnson of The Boston Globe writes that MIT researchers have developed a new way to enlarge microscopic lab samples to allow for more-detailed imaging of brain cells. The new technique “may offer an inexpensive way for people to examine fine cellular structures at a detailed level using off-the-shelf ingredients.”

Associated Press

A team of MIT researchers has devised a new method for obtaining super-high resolution images from lab microscopes, writes Malcolm Ritter for the AP. The researchers found that by permeating a tissue sample with a specialized version of sodium polyacrylate they were able to enlarge the sample, making them easier to image. 

Boston Globe

Led by Professor Eric Alm, a team of researchers plans to analyze sewage in Cambridge to screen for data on disease and drug use, reports Michael Fitzgerald for The Boston Globe. “Sewage is really an unexploited source of rich information about human activities,” says Alm.

The Daily Beast

“There’s an enormous richness of information by looking in the water that’s indicative of what’s going in a city in a real-time fashion,” says Prof. Eric Alm in an interview with Wudan Yan of The Daily Beast of his idea to examine public health by tracking the transmission of pathogens in sewers. 

WBUR

WBUR’s Deborah Becker and Lynn Jolicoeur report on the new MIT-MGH partnership aimed at developing better tools to treat disease. Prof. Arup Chakraborty hopes the collaboration will allow researchers to take risks. “Safe ideas are often not the transformative ones,” he says. 

Scientific American

Brendan Borrell writes for Scientific American about how MIT researchers have engineered the DNA of E.coli to detect and record environmental information. “Building gene circuits requires not only computation and logic, but a way to store that information,” says Prof. Timothy Lu. “DNA provides a very stable form of memory and will allow us to do more complex computing tasks.”

New Scientist

MIT engineers have altered the DNA of E.coli so that it can store memories, reports Colin Barras for New Scientist. The research could “pave the way for cellular biographers that can be inserted into our bodies for the inside scoop on our health,” Barras explains. 

Nature

Nature highlights the top science news of the week, including the new interdisciplinary center at MIT aimed at examining the microbiome. “The center will initially focus on inflammatory bowel disease, but organizers hope to eventually broaden the scope to diseases such as multiple sclerosis, arthritis and autism,” Nature reports. 

Boston Globe

In a piece for The Boston Globe, Meredith Goldstein writes that Institute Professor Robert Langer received a Kyoto Prize at a ceremony in Japan for his work with tissue engineering.