John Markoff writes for The New York Times about a new technique for observing minuscule features in biological samples developed by Prof. Ed Boyden and his colleagues. The researchers “were able to increase the physical size of cultured cells and tissue by as much as five times while still preserving their structure,” Markoff explains.
Rebecca Jacobson of the PBS NewsHour reports that MIT researchers have developed a new technique to enlarge tissue samples, allowing scientists to create high-resolution images of specimens. Prof. Ed Boyden explains that “now you can see tiny structures with your own eyes.”
Carolyn Johnson of The Boston Globe writes that MIT researchers have developed a new way to enlarge microscopic lab samples to allow for more-detailed imaging of brain cells. The new technique “may offer an inexpensive way for people to examine fine cellular structures at a detailed level using off-the-shelf ingredients.”
A team of MIT researchers has devised a new method for obtaining super-high resolution images from lab microscopes, writes Malcolm Ritter for the AP. The researchers found that by permeating a tissue sample with a specialized version of sodium polyacrylate they were able to enlarge the sample, making them easier to image.
Led by Professor Eric Alm, a team of researchers plans to analyze sewage in Cambridge to screen for data on disease and drug use, reports Michael Fitzgerald for The Boston Globe. “Sewage is really an unexploited source of rich information about human activities,” says Alm.
“There’s an enormous richness of information by looking in the water that’s indicative of what’s going in a city in a real-time fashion,” says Prof. Eric Alm in an interview with Wudan Yan of The Daily Beast of his idea to examine public health by tracking the transmission of pathogens in sewers.
WBUR’s Deborah Becker and Lynn Jolicoeur report on the new MIT-MGH partnership aimed at developing better tools to treat disease. Prof. Arup Chakraborty hopes the collaboration will allow researchers to take risks. “Safe ideas are often not the transformative ones,” he says.
Brendan Borrell writes for Scientific American about how MIT researchers have engineered the DNA of E.coli to detect and record environmental information. “Building gene circuits requires not only computation and logic, but a way to store that information,” says Prof. Timothy Lu. “DNA provides a very stable form of memory and will allow us to do more complex computing tasks.”
MIT engineers have altered the DNA of E.coli so that it can store memories, reports Colin Barras for New Scientist. The research could “pave the way for cellular biographers that can be inserted into our bodies for the inside scoop on our health,” Barras explains.
Nature highlights the top science news of the week, including the new interdisciplinary center at MIT aimed at examining the microbiome. “The center will initially focus on inflammatory bowel disease, but organizers hope to eventually broaden the scope to diseases such as multiple sclerosis, arthritis and autism,” Nature reports.
In a piece for The Boston Globe, Meredith Goldstein writes that Institute Professor Robert Langer received a Kyoto Prize at a ceremony in Japan for his work with tissue engineering.
Thomas Burton of The Wall Street Journal writes that MIT researchers were among those awarded the first research grants under President Obama’s new BRAIN Initiative. Burton writes that one of the MIT grants will go toward “determining which exact brain circuits are involved in generating short-term memories that influence decisions.”
Boston Globe reporter Deborah Kotz writes that MIT researchers have been awarded new grants from the National Institutes of Health to further brain research. “Biophysicist Alan Jasanoff received a grant to develop imaging agents for functional MRI imaging that would target the flow of calcium into and out of brain cells,” writes Kotz of one of the MIT grants.
MIT neuroscientists were among the recipients of new grants for brain research from the National Institutes of Health, reports Jon Hamilton for NPR. Hamilton explains that as part of one grant, “Researchers from the Massachusetts Institute of Technology will try to adapt functional MRI so that it can show the activity of individual brain cells.”
Loren Grush of Popular Science writes about a new type of antibiotic developed by MIT researchers that could help kill drug-resistant bacteria. “[T]he team developed their own gene-editing system, capable of turning off certain bacterial genes that spur antibiotic resistance,” Grush explains.