Researchers from MIT and other institutions have developed a new model for autism research that could enable new therapies and treatments, reports the Xinhua news agency. The model could “provide a basis for a deeper understanding of the neurobiological mechanisms of autism and the development of more transformative therapeutics.”
Writing for Scientific American, Prof. Bob Langer examines how breakthroughs in biotechnology and materials science are enabling more personalized and effective treatments for patients. Langer highlights how by “engineering polymers that offer smart delivery systems, we can target specific parts of the body. This limits exposure and therefore adverse effects, offering more effective and precise treatment.”
President Emerita Susan Hockfield discusses her new book, “The Age of Living Machines,” her work as a neuroscientist, and the future of science and technology during a curated lunch conversation with HUBweek and Boston.com. Hockfield explains that a revolution spurred by the convergence of biology with engineering will lead to new technologies built by biology.
In an excerpt from her new book published in The Wall Street Journal, President Emerita Susan Hockfield explores how the convergence between biology and engineering is driving the development of new tools to tackle pressing human problems. Hockfield writes that for these world-changing technologies to be realized requires “not only funding and institutional support but, more fundamentally, a commitment to collaboration among unlikely partners.”
MIT researchers have developed a new system to 3-D print scaffolding for biological cultures, making it possible to grow uniform cells with specific functions, reports The Economist. “This discovery could help those trying to find ways of encouraging stem cells to generate tissue and organs for transplant.”
President Emerita Susan Hockfield speaks with Jim Braude of WGBH’s Greater Boston about her book, “The Age of Living Machines.” “We are looking at a population of over 9.7 billion by 2050,” explains Hockfield. “We are not going to get there without war or epidemics or starvation if we don’t develop technologies that will allow us to provide energy, food, water, health and health care sustainably.”
Prof. Eric Alm speaks with New Scientist reporter Elie Dolgin about his work building a repository of gut microbes. “What we are doing is taking a snapshot of the biodiversity of human gut microbes on Earth today,” Alm explains, “and then preserving that for future generations so that we always have the biodiversity that co-evolved with us stored somewhere.”
ABC News spotlights how MIT researchers have found that a lobster’s membrane could serve as inspiration for developing new forms of body armor. “The membrane on a lobster’s underbelly is as strong as the rubber on car tires. It could be used as a guide for body armor that allows more mobility without sacrificing protection.”
Newsweek reporter Hannah Osborne writes that MIT researchers have found that a lobster’s membrane, which protects its underbelly, is made of one of the toughest hydrogels in the world. “Its strength and flexibility,” Osborne explains, could “make it an ideal material to use as a blueprint for body armor.”
Washington Post reporter Peter Holley writes that MIT researchers have found that the soft membrane covering a lobster’s joints and abdomen is as tough as industrial rubber. The researchers discovered, “lobsters could offer a solution to the problem plaguing most modern body armors: the more mobility an armor offers, the less it protects the wearer’s body.”
Dr. Francis Collins, director of the National Institutes of Health, spotlights how MIT researchers have developed a new imaging technique that can “provide us with jaw-dropping views of a wide range of biological systems.” Collins writes that the new “imaging approach shows much promise as a complementary tool for biological exploration.”
MIT researchers developed a new technique to make a more effective and precise CRISPR gene editing system, reports Eileen Drage O’Reilly for Axios. The system uses the new enzyme Cas12b, which has a “small size and precise targeting [that] will enable it to be used for in vivo applications in primary human cells,” O’Reilly explains.
Popular Mechanics reporter David Grossman writes that MIT researchers have developed a new imaging technique that allows entire neural circuits in the brain to be explored at speeds 1,000 times faster than currently available methods. The new technique could allow scientists to “spot where brain diseases originate or even the basics of how behavior works.”
MIT researchers have developed a new high-resolution technique to image the brain that could be used to create more precise maps of the brain and identify the causes of brain disease, reports Megan Thielking for STAT. “If we can figure out exactly where diseases begin,” explains Prof. Edward Boyden, “that could be pretty powerful.”
Guardian reporter Ian Sample writes that MIT startup Synlogic are developing a “living” medicine” made from genetically modified bugs. “By engineering these bacteria, we are able to control how they operate in the human gastrointestinal tract,” says Caroline Kurtz of Synlogic. “It allows us to think about many other diseases where you may need to produce something beneficial, or remove something that is toxic for the patient.”