MIT researchers developed a new technique to make a more effective and precise CRISPR gene editing system, reports Eileen Drage O’Reilly for Axios. The system uses the new enzyme Cas12b, which has a “small size and precise targeting [that] will enable it to be used for in vivo applications in primary human cells,” O’Reilly explains.
Popular Mechanics reporter David Grossman writes that MIT researchers have developed a new imaging technique that allows entire neural circuits in the brain to be explored at speeds 1,000 times faster than currently available methods. The new technique could allow scientists to “spot where brain diseases originate or even the basics of how behavior works.”
MIT researchers have developed a new high-resolution technique to image the brain that could be used to create more precise maps of the brain and identify the causes of brain disease, reports Megan Thielking for STAT. “If we can figure out exactly where diseases begin,” explains Prof. Edward Boyden, “that could be pretty powerful.”
Guardian reporter Ian Sample writes that MIT startup Synlogic are developing a “living” medicine” made from genetically modified bugs. “By engineering these bacteria, we are able to control how they operate in the human gastrointestinal tract,” says Caroline Kurtz of Synlogic. “It allows us to think about many other diseases where you may need to produce something beneficial, or remove something that is toxic for the patient.”
Forbes contributor Angelica Krystle Donati highlights a recent presentation by Prof. Robert Langer, in which he shared his experience founding more than 40 startups.
MIT researchers have developed a new app called Perdix that allows users to create 2-D nanostructures using DNA strands, reports Jesus Diaz for Fast Company. Engineers could use Perdix to print nanoscale parts for applications in cell biology, photonics, quantum sensing and computing, Diaz explains.
Forbes contributor David DiSalvo highlights Prof. Alan Jasanoff’s book, “The Biological Mind: How Brain, Body and Environment Collaborate to Make Us Who We Are” on his list of the must-read brain books of 2018. “Rather than being another assessment of what the brain does, this one is about what it is—and more interestingly what it is not,” writes DiSalvo.
Boston Globe reporter Martin Finucane writes that MIT researchers have developed a new way to fabricate tiny objects. “The researchers are currently able to create objects that are around 1 cubic millimeter, with features as small as 50 nanometers,” Finucane explains. “The tiny structures could be useful in fields from optics to medicine to robotics.”
Popular Mechanics reporter David Grossman writes about a new fabrication technique developed by MIT researchers that allows for regular-sized objects to be shrunk down to the nanoscale. Grossman explains that the new method, “takes a technique currently used to make images of brain tissue larger and reverses it.”
Inside Science reporter Yuen Yiu writes that MIT researchers have developed a new technique for producing nanoscale structures using a 3-D printing method that shrinks objects. Yiu explains that the new technique operates by “first creating a bigger structure inside of a gel, then shrinking the gel, which brings the structure down to one-thousandth the volume of the original.”
MIT researchers have developed a new method to shrink 3-D printed objects, reports Douglas Heaven for New Scientist. The technique can be used to create a wide variety of shapes using different materials. “In the 1970s hobbyists built their own computers at home,” explains Prof. Edward Boyden. “Maybe people can now make their own chips.”
MIT researchers have engineered wasp venom to kill bacteria, reports Chukwuma Muanya for The Guardian. The researchers found that the altered peptides wiped out the antibiotic-resistant bacteria Pseudomonas aeruginosa within four days.
Forbes reporter Fiona McMillan writes that MIT researchers have engineered an anti-bacterial peptide found in wasp venom in an effort to create a new antibiotic. McMillan writes that the researchers, “gained new insight into which structural attributes work best, either alone or in combination. In this way, they were able to tweak the peptide’s structure to obtain optimal function.”
MIT researchers have repurposed the toxic venom found in wasps to create a new drug that could potentially be used to kill bacteria, reports the Xinhua news agency. “The venom-derived peptide is believed to kill microbes by disrupting bacterial cell membranes,” Xinhua explains.
Boston Herald reporter Jordan Graham writes that MIT researchers have used the venom from a South American wasp to engineer a new type of antibiotic. “The idea here is to take that very well-crafted toxin and turn it into something that can be useful for humans and our society,” explains César de la Fuente Nunez, a postdoc at MIT.