Biological engineering

For Scientific American’s special section “The Young American Scientists,” Prof. Feng Zhang speaks with Tara Haelle about the importance of investing in science and education, noting that “American science has long been the strongest engine of discovery and innovation in the world.” Zhang shares: “I’m fortunate to work with extraordinary students and postdocs, but the infrastructure that lets them do their best work is under real stress: funding instability..., immigration uncertainty for international scientists and an erosion of public trust in expertise. We can lose the lead rapidly if we do not protect our innovation ecosystem.” 

For the Scientific American special section “The Young American Scientists,” Institute Prof. Robert Langer speaks with Megha Satyanarayana about the “spectacular” history of American innovation and education, and why he feels it’s important to celebrate scientific achievements in the same way we honor celebrities and sports stars. “I’m just a big believer in the resilience of people,” says Langer. “I look at the history of American innovation and education over the past 250 years, and it’s been spectacular. We’ve had world wars, you know, we’ve had depressions, and people keep persisting and keep learning. They keep discovering and they keep inventing.”

Visiting Scientist Alice Stanton speaks with Scientific American reporter Tanya Lewis about her work developing miBrain, a 3D model of the human aimed at helping scientists “better understand neurological diseases such as Alzheimer’s and Parkinson’s so researchers can develop personalized treatments for them.” Says Stanton of the need for stable support for scientific research: “When we have a loved one who gets sick, we want a treatment—we want something to cure them. It doesn’t come out of thin air.”

Nature reporter Jyoti Madhusoodanan features Prof. Regina Barzilay and Prof. James Collin’s work developing AI tools aimed at accelerating the process of drug discovery and tackling the growing problem of antibiotic resistance. Barzilay notes that the goal of AI-based drug design is not to have the perfect method, but to find working solutions to the antibiotic-resistance crisis. “To me, the art is really in taking the tools we currently have, which are already doing quite a bit, and translating them into something which is useful in clinic,” she explains. 

Nature reporter Rachel Fieldhouse spotlights graduate student Lauren 'Ren' Ramlan’s work integrating the video game Doom into her research. Ramlan used “Escherichia coli bacteria to display a few frames of Doom,” explains Fieldhouse. “She attached a fluorescent protein to the bacterial cells that could be turned on or off, making them act like black and white pixels on a screen. She then translated and compressed the first few frames of Doom into black-and-white versions that matched the plate growing the cells. Ramlan says the project shows what living things can be engineered to do, and that bacteria are probably not suitable for computing or displaying images.” 

Mitali Chowdhury '24 has been named a 2026 Gates Cambridge Scholar, reports Michael T. Nietzel for Forbes. Beginning this fall, Chowdhury will pursue “a PhD in Sensor Technologies and Applications [at the University of Cambridge]” explains Nietzel. “Her research will focus on CRISPR-based diagnostics to assess antimicrobial resistance, with the goal of expanding equitable access to health care.” 

Prof. Angela Belcher and Prof. Sangeeta Bhatia chat with Edgar B. Herwick III of GBH’s The Curiosity Desk about their efforts aimed at improving diagnostics for ovarian cancer. “We now know that ovarian cancer doesn’t originate in the ovaries. About 80% of the time, ovarian cancer starts in the fallopian tubes, but it can sit there as this precancerous lesion,” explains Belcher. “There’s new technologies that can be invented and developed to detect it much earlier, because if it’s detected earlier…there’s such an opportunity to make an impact.”  

Prof. James Collins and his colleagues are using AI to develop new compounds to combat the growing problem of antibiotic resistant bacteria, reports Lisa M. Krieger for the San Francisco Chronicle. Thus far, “Collins and his colleagues have synthesized several compounds that combat hard-to-treat infections of gonorrhea and MRSA,” writes Krieger. “These techniques are also being harnessed to fight diseases, like cancer, lupus and arthritis.” 

Prof. James Collins speaks with Financial Times reporter Patrick Temple-West about his work using AI to design new antibiotic compounds to combat drug-resistant bacteria. “At present, the [AI] models are doing quite well at designing compounds that can attack in a Petri dish,” says Collins. 

Researchers at MIT are using AI systems to design new molecules for potential antibiotics, research that is “aimed at the growing challenge of antibiotic-resistant infections,” reports Adele Peters for Fast Company. “The number of resistant bacterial pathogens has been growing, decade upon decade,” says Prof. James Collins. “And the number of new antibiotics being developed has been dropping, decade upon decade.” 

Researchers at MIT have developed “artificial tendons made from tough, flexible hydrogel,” reports Neetika Walter for Interesting Engineering. “These rubber band–like connectors dramatically boost the speed, strength, and durability of muscle-powered robots,” explains Walter. 

Prof. Bryan Bryson speaks with Chris Smith on The Naked Scientists podcast about his efforts to find targets for a new tuberculosis vaccine, as the current version, which is very effective in children, does not sufficiently protect adolescents and adults. “Right now, we only have one TB vaccine that's over 100 years old,” said Bryson.  “And for me as an engineer, if somebody tells you there's a 100 year old technology that doesn't work the way that you want it to, you want to say, let's build a better one.” 

Philadelphia Inquirer reporter Maggie Prosser spotlights senior Alice Hall, who was selected as one of the 2026 Rhodes Scholars. “Never stop trying to learn, especially from the people around you,” says Hall. “You don’t have to be a Rhodes scholar to change the world. Just be yourself.” 

Vivian Chinoda '25, Alice Hall, Sofia Lara, and Sophia Wang '24 have been named 2026 Rhodes Scholars, reports Michael Nietzel for Forbes. “This class of U.S .Rhodes Scholars will pursue studies across the social sciences, humanities, and biological and physical sciences,” writes Nietzel. 

Boston 25 spotlights Vivian Chinoda '25, Alice Hall, Sofia Lara, and Sophia Wang '24 who have been named 2026 Rhodes Scholars. “The students will attend the University of Oxford as part of the Rhodes scholar program, which awards more than 100 scholarships worldwide each year for students to pursue two to three years of graduate studies.”