Boston Globe reporter Jonathan Saltzman writes about how MIT alumnus Bernat Olle’s startup, Vedanta Biosciences, Inc., is looking to “collect a sample of every type of bacteria that lives in the gut.” The hope is to one day use what’s learned from this ‘library’ to help treat diseases.
MIT researchers have discovered that probiotics can prevent cholera and treat early stage cases of the disease, reports Laney Ruckstuhl for The Boston Globe. The findings, led by Prof. James Collins, “could have implications for other diseases as well because scientists were previously unaware that bacterial infections could be vulnerable to naturally occurring probiotics,” notes Ruckstuhl.
CNBC reporter Thomas Catenacci writes that researchers at the MIT Design Lab are collaborating with Puma to develop a new shoe made with bacteria that can react to how the wearer is feeling. They presented their ‘biodesigns’ at Milan Design Week, notes Catenacci, explaining that the shoe’s material can learn “a user's specific heat patterns and opens up ventilation based on those user-specific heat patterns.”
Using specially engineered E. coli bacteria and electronics that fit into an ingestible pill, MIT researchers have created a device that can detect internal diseases and send wireless alerts, reports Karen Kaplan for The Los Angeles Times. The device could eliminate the need for colonoscopies, which alter “the physiology inside the intestines, potentially masking signs of disease,” explains Kaplan.
USA Today reporter Sean Rossman writes about how MIT researchers have created an ingestible sensor that can monitor the digestive tract and send information to a smartphone or tablet about a person’s health. Rossman explains that the device, “can detect blood in the stomach, something that would otherwise require an endoscopy and sedation.”
MIT researchers have developed an ingestible capsule that uses genetically engineered bacteria to detect potential health problems, reports Carla Johnson for the Associated Press. The researchers hope the capsule could eventually be used to, “find signs of ulcers, inflammatory bowel disease or even colon cancer.”
Wired reporter Megan Molteni writes that a team of MIT researchers has developed an ingestible sensor that could spot gastrointestinal issues. The sensor contains, “millions of genetically engineered glowing bacteria inside a AAA-battery-sized capsule,” Molteni explains.
Writing for the Boston Herald, Lindsay Kalter reports that MIT scientists have built an ingestible capsule that could allow doctors to diagnose gastrointestinal diseases without invasive procedures. Graduate student Mark Mimee explains that the device, “sets the stage for having a pill that can give you a big biochemical profile of the gut related to various diseases.”
Popular Mechanics reporter David Grossman writes that a new ingestible medical device developed by MIT researchers could monitor the health of the human gut. Calling the project “a true team effort,” Grossman explains that it required expertise in biological engineering techniques, electronic circuit design, materials, and gastroenterology.
MIT spinout Ginkgo Bioworks is highlighted on the 2018 CNBC Disruptor 50 list, reports CNBC’s Andrew Zaleski. Zaleski notes that Ginkgo Bioworks, “has developed an automated process for combining genetic parts that has made it the largest designer of printed DNA in the world. That breakthrough has positioned the start-up to change the face of a variety of industries.”
Postdoc Gabriel Leventhal has created a project to track how the microbes in a sourdough starter change as it gets shared around the world, writes Alex Kingsbury of The Boston Globe. To track the starter, “Herman,” each descendant is given a unique name and number before the samples are returned to the lab to track how the microbes evolve, Kingsbury explains.
Synlogic, founded by Prof. Jim Collins and Associate Prof. Tim Lu, is programming probiotic bacteria to treat certain genetic or acquired metabolic disease, reports Robin Seaton Jefferson for Forbes. One product is used for people whose bodies can’t maintain a healthy level of ammonia and “has been specifically engineered to convert the excess ammonia to a harmless metabolite,” explains Seaton Jefferson.
MIT researchers have discovered a new family of viruses in the ocean that appears to play a key role in ocean ecosystems and could help provide insights on how viruses evolve, reports Marin Finucane for The Boston Globe. Finucane explains that the findings could also lead to, "a better understanding of human biology.”
MIT spinout Ginkgo Bioworks has not only maintained its founding members, but also recently raised $275 million from investors, writes Matthew Herper for Forbes. Herper predicts that excitement surrounding synthetic biology companies will continue because “private money is getting excited about the idea of designing biology.”
A new study by MIT researchers provides evidence that antibiotics can change the body’s chemistry and make it more hospitable to bacteria, reports Melinda Wenner Moyer for Scientific American. “We suspect that the strength of this effect will really depend on the type of infection and types of antibiotics used,” explains postdoc Jason Yang.