How an influx of salt may affect microbial ecosystems
As sea levels rise and saltwater seeps into freshwater, stressed aquatic populations may retain overall growth even as diversity declines, MIT scientists find.
Why are some bacterial genes high in purines?
In certain species of bacteria, the answer lies in shielding RNA transcripts from a quality-control factor called Rho. Understanding the requirements for expressible sequences is critical for expression engineering of therapeutic agents.
How neurons sense bacteria in the gut
Neural interaction with bacteria has important effects on animal brains. A new study investigates how neurons sense bacteria by revealing, in nematodes, the bacterial signals that a key neuron detects.
Slice and dice
SNIPE, a newly characterized biological defense system, directly protects bacteria by chopping up invading viral DNA.
How bacteria suppress immune defenses in stubborn wound infections
Study finds a common bacterium can suppress the body’s early warning system in wounds, causing infections to persist and create an environment that allows other bacteria to take hold.
CryoPRISM: A new tool for observing cellular machinery in a more natural environment
The method allows researchers to observe biomolecular complexes in a quick, accurate, and budget-friendly way, providing new insights into bacterial protein synthesis.
Ocean bacteria team up to break down biodegradable plastic
MIT researchers uncovered the roles of bacterial species from the environment as they consume biodegradable plastic.
New sensor sniffs out pneumonia on a patient’s breath
The technology could enable fast, point-of-care diagnoses for pneumonia and other lung conditions.
Understanding how “marine snow” acts as a carbon sink
A new study finds hitchhiking bacteria dissolve essential ballast in ubiquitous “snow” particles, which could counteract the ocean’s ability to sequester carbon.
Nitrous oxide, a product of fertilizer use, may harm some soil bacteria
While some N2O is produced naturally at the plant root, agricultural practices can increase its levels, to the detriment of some microbes that support plant growth.
3 Questions: Using AI to accelerate the discovery and design of therapeutic drugs
Professor James Collins discusses how collaboration has been central to his research into combining computational predictions with new experimental platforms.
Bryan Bryson: Engineering solutions to the tough problem of tuberculosis
By analyzing how Myobacterium tuberculosis interacts with the immune system, the associate professor hopes to find new vaccine targets to help eliminate the disease.
3 Questions: Using computation to study the world’s best single-celled chemists
Assistant Professor Yunha Hwang utilizes microbial genomes to examine the language of biology. Her appointment reflects MIT’s commitment to exploring the intersection of genetics research and AI.
MIT study finds targets for a new tuberculosis vaccine
Using these antigens, researchers plan to develop vaccine candidates that they hope would stimulate a strong immune response against the world’s deadliest pathogen.
AI maps how a new antibiotic targets gut bacteria
MIT CSAIL and McMaster researchers used a generative AI model to reveal how a narrow-spectrum antibiotic attacks disease-causing bacteria, speeding up a process that normally takes years.