MIT researchers have discovered how propofol, a commonly used anesthetic, works on the brain, reports Francesca Benson for IFL Science. The research studied “the differences between an awake brain and one under anesthesia by looking at the stability of the brain’s activity,” writes Bensen.
MIT scientists have discovered how propofol, a commonly used anesthetic, induces unconsciousness, reports Adam Kovac for Gizmodo. “The new research indicates that [propofol] works by interfering with a brain’s ‘dynamic stability’ – a state where neurons can respond to input, but the brain is able to keep them from getting too excited,” explains Kovac.
A study by Prof. Emery Brown suggests that the combination of Covid-19 and anesthesia could prompt the human brain into a state of quiet that can last weeks or months, similar to how turtles quiet their neurons to survive winter, reports Carl Zimmer for The New York Times. The findings “might point to new ways to save people from brain damage: by intentionally putting people into this state, rather than doing so by accident.”
Wired reporter Max Levy spotlights Prof. Emery Brown and Earl Miller’s research examining how neurons in the brain operate as “consciousness emerges and recedes—and how doctors could better control it.” Levy writes that “Miller and Brown's work could make anesthesia safer, by allowing anesthesiologists who use the EEG to more precisely control drug dosages for people who are unconscious.”