Chemists reveal how tau proteins form tangles
Two types of tau proteins mix together in a nearly random way to generate the tangles seen in the brains of Alzheimer’s patients.
Two types of tau proteins mix together in a nearly random way to generate the tangles seen in the brains of Alzheimer’s patients.
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.
The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia.
The visual cortex stores and remembers individual images, but mice can’t recognize image sequences without guidance from the hippocampus.
To quickly express learning and memory genes, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows.
How 3D-printed models of neuronal axons could accelerate development of new therapies to treat neurodegenerative disorders.
Selective global honor supports early-career scientists and engineers in taking on new pursuits.
New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.
The gene variant disrupts lipid metabolism, but in cell experiments the effects were reversed by choline supplements.
Speakers describe studies to address Alzheimer’s disease, sleep apnea, and to advance fundamental discoveries in cell and chromosome biology.
During her time at MIT, senior Ayesha Ng’s interests have expanded from cellular biology to the social systems that shape public health.
Immuneering uses bioinformatics to develop new medicines while also helping large pharmaceutical companies improve their treatments.
Astrocytes with the APOE4 gene variant show deficits of a key cellular function, but overexpressing the gene PICALM overcame the defect.
MIT researchers pinpoint mechanism and demonstrate that drugs could help.
Reactivating an enzyme that promotes DNA repair can help to reverse age-related cognitive decline in mice.