Institute for Medical Engineering and Science (IMES)

MIT chemical engineers have developed a new series of lipid nanoparticles to deliver RNA vaccines.

Delivery system can make RNA vaccines more powerful

Vaccines packaged in novel nanoparticles could offer a new way to fight cancer and infectious diseases.

September 30, 2019

Depiction of a soft robotic device known as a dynamic soft reservoir (DSR)

Soft robotics breakthrough manages immune response for implanted devices

Discovery could enable longer-lasting and better-functioning devices — including pacemakers, breast implants, biosensors, and drug delivery devices.

September 4, 2019

MIT and Boston Children’s Hospital researchers have devised a minimally invasive way to monitor intracranial pressure in patients suffering from traumatic brain injuries or infectious diseases. Current techniques for measuring pressure within the brain are so invasive that the measurement is only performed in high-risk patients.

A much less invasive way to monitor pressure in the brain

New technique could help doctors determine whether patients are at risk from elevated pressure.

August 23, 2019

MIT engineers created a DNA-acrylamide gel that can be degraded by DNA-editing enzymes. At right, the gel is broken down after two hours of exposure to a DNA "trigger sequence." At left, the gel is exposed to DNA that doesn't contain the trigger sequence, so it remains intact.

Using CRISPR to program gels with new functions

Smart materials change properties in response to specific DNA sequences; could be used in a variety of devices.

August 22, 2019

Yearlong hackathon engages nano community around health issues

Hacking Nanomedicine kicks off a series of events to develop an idea over time.

August 9, 2019

MIT researchers have developed a new model of gene control, in which the cellular machinery that transcribes DNA into RNA forms specialized droplets called condensates.

Study furthers radically new view of gene control

Along the genome, proteins form liquid-like droplets that appear to boost the expression of particular genes.

August 8, 2019

Jaume Plensa sculpture, "The Alchemist" on MIT's campus

School of Engineering second quarter 2019 awards

Faculty members recognized for excellence via a diverse array of honors, grants, and prizes over the past quarter.

July 30, 2019

A course called Machine Learning for Healthcare introduces students to the technical and ethical challenges of using automated tools to diagnose and treat patients.

Want to know what software-driven health care looks like? This class offers some clues.

A course that combines machine learning and health care explores the promise of applying artificial intelligence to medicine.

July 24, 2019

MIT engineers have devised a way to incorporate crystallized immunosuppressant drugs into devices carrying encapsulated islet cells, which could allow them to be implanted as a long-term treatment for diabetes.

A better way to encapsulate islet cells for diabetes treatment

Crystallized drug prevents immune system rejection of transplanted pancreatic islet cells.

June 24, 2019

Structure-based network analysis transforms HIV proteins into networks used to identify T cell targets resistant to mutation.

Structure of T cell epitopes a decisive factor in natural HIV control, study finds

Researchers apply network theory to HIV protein structure, uncovering a vital link between connectivity and protective immune response.

May 13, 2019

MIT biological engineers used a novel machine-learning approach to discover a mechanism that helps certain antibiotics kill bacteria.

Painting a fuller picture of how antibiotics act

Machine learning reveals metabolic pathways disrupted by the drugs, offering new targets to combat resistance.

May 9, 2019

School of Engineering first quarter 2019 awards

Faculty members recognized for excellence via a diverse array of honors, grants, and prizes over the last quarter.

May 3, 2019

MIT engineers have designed a magnetic microrobot that can help push drug-delivery particles into tumor tissue (left). They also employed swarms of naturally magnetic bacteria to achieve the same effect (right).

Nanoparticles take a fantastic, magnetic voyage

Tiny robots powered by magnetic fields could help drug-delivery nanoparticles reach their targets.

April 26, 2019

Hospitals in highlighted regions have contributed data to the Global Open Source Severity of Illness Score, or GOSSIS.

A new way to calculate global intensive care unit mortality risk

The GOSSIS algorithm was developed using data from hospitals around the world to spur greater multi-center collaboration and improved benchmarking.

March 8, 2019

Researchers have released a repository of more than 350,000 detailed chest X-rays, which is free and open to academic, clinical, and industrial investigators.

MIMIC Chest X-Ray database to provide researchers access to over 350,000 patient radiographs

A new database of images could pave a path for algorithmic models that ensure accurate diagnoses of conditions like pneumonia.

February 1, 2019

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