Biology

Writing for Forbes, Arvid Ernst Gollwitzer, a research scholar at the Broad Institute of MIT and Harvard, spotlights FINGERS-7B, an AI foundation model for Alzheimer’s prevention his research team developed at MIT. “By analyzing signals spanning everything from genetic risk factors to long-term environmental exposures, the model detects patterns that no single-domain approach could find,” writes Gollwitzer. “These patterns, which we call multi-omic precision signatures, represent a new kind of biomarker for gauging early disease risk.” 

Sonia Vallabh, Director of Prion Therapeutic Science at the Broad Institute of MIT and Harvard, speaks to Nature’s Josie Glausiusz about her journey co-leading an initiative to develop preventive drugs for prion disease, a rare, lethal neurodegenerative disease that is caused by misfolded proteins that kill neurons. “In pre-symptomatic people at risk, if we can lower the amount of normal protein, I’m hoping we can delay or even prevent the formation of the first misfolded prion,” says Vallabh.  

Prof. Sebastian Lourido speaks to Boston Globe reporter Lindsay Crudele about the safety of local produce amidst the current cyclospora outbreak. “There are many features of local agriculture that are less susceptible to the spread of these kinds of diseases,” says Lourido. 

The life and work of the late Nobel laureate Prof. Susumu Tonegawa, founding director of MIT’s Picower Institute for Learning and Memory, is spotlighted by The New York Times’ Dylan Loeb McClain. “Few scientists have reshaped our understanding of biology as profoundly,” says Prof. Myriam Heiman, director of the Picower Institute. “His intellectual fearlessness, extraordinary creativity and relentless pursuit of fundamental questions opened entirely new frontiers in both immunology and neuroscience.” 

A new study by MIT researchers finds high-fat, low-carbohydrate ketogenic diets may increase the risk of certain intestinal cancers, writes Newsweek’s Daniella Gray. “The researchers say future studies will be needed to better understand how specific dietary fats influence cancer risk and whether modifying the composition of ketogenic diets could reduce potential harms while preserving any health benefits,” writes Gray.  

Prof. Brett McGuire joins Peter O'Dowd, host of WBUR’s “Here & Now,” to discuss astronomers’ discovery of Erythrulose, the sugar found in raspberries, in clouds of gas about 25,000 light-years away from Earth. “By a chemist's formal definition this is a sugar—given its structure, the way its atoms are bonded together,” says McGuire. "It’s not the sort of sugar that we think of as involved in making things sweet for us. But it is still a sugar in that it is a compound that stores energy and is involved in biological processes that access that energy and allow it to be used by living organisms." 

MIT researchers found that the keto diet, which emphasizes low carbs and sugar, could increase the risk of tumors in the small intestine, explains New York Post reporter Allie Yang. The researchers found that “cells burning fat (from ketosis) start a chain reaction which leads to stem cells multiplying rapidly, increasing the chance they go out of control and become cancer,” Yang explains.  

The Guardian’s David Kohn points to a study by Prof. Siniša Hrvatin that proposes targeting the preoptic area of the brain to induce torpor (a hibernation-like state) as a solution for astronauts to survive long term space travel. “Key aspects of the circuit appear to be conserved across different animals,” says Hrvatin. “I think we can use it to modify metabolism.” 

MIT researchers have developed a non-invasive, wearable pacemaker that stimulates the heart using ultrasound, writes Physics World reporter Tami Freeman. “For cardiac pacing, we envisage that the final goal of NUP [Non-Invasive Ultrasound Pacemaker] technology is to be a permanent alternative to a long-term implanted pacemaker,” says Prof. Xuanhe Zhao. “More broadly, we are interested in expanding ultrasound-enabled bioelectronic medicine beyond cardiac pacing toward other organs and therapeutic applications where non-invasive, spatially precise modulation could have clinical impact.” 

MIT researchers have found that colon cancer cells can “change their identity, allowing them to travel through the body and form new tumors,” reports Daniella Gray for Newsweek. The findings could point to future treatments that can prevent metastasis—the leading cause of death for colorectal cancer patients, Gray explains. 

New York Times reporters Gina Kolata and Rebecca Robbins highlight how university researchers at MIT and Harvard laid the groundwork for the development of a new treatment for pancreatic cancer that “could wind up being the most significant advance in cancer treatment in 15 years, since the arrival of immunotherapy.” They write: “In 1982, Robert Weinberg, a scientist at MIT, made one of the seminal discoveries about how RAS genes fuel some cancers.” 

Two new studies from researchers at MIT and elsewhere have described “the machine-learning algorithms they developed to screen bacterial genomes and identify proteins that are involved in protecting the microorganisms against viral invaders,” reports Miryam Naddaf for Nature. “There’s a hope that maybe there’s a next generation of molecular tools that would come from some of these new systems,” says Prof. Michael Laub. 

According to the 2026 QS World University Rankings, MIT has been earned a No. 1 global ranking in 12 subject areas, including chemical engineering; chemistry; civil and structural engineering; computer science and information systems; data science and artificial intelligence; electrical and electronic engineering; engineering and technology; linguistics; materials science; mechanical, aeronautical, and manufacturing engineering; mathematics; and physics and astronomy, reports Michael T. Nietzel for Forbes.

Vogue editor Lisa Wong Macabasco spotlights “Lighten Up! On Biology and Time,” a new exhibit at the MIT Museum that “traces the rhythms of life itself: circadian patterns, light’s command over the body, and the delicate architecture of alertness and rest.” The exhibit features “18 works that blend science and art, from immersive soundscapes to visualizations of circadian patterns and reflective spaces where you observe your own heartbeat and alertness in new ways,” explains Macabasco. 

Surface reporter David Graver highlights “Lighten Up! On Biology and Time,” an MIT Museum exhibit exploring the “connection between living creatures and circadian rhythm through 18 contemporary artworks and experiential environments.” "The ‘Lighten Up!’ exhibition begins with awakening and ends with sleep,” says MIT Museum Director Michael John Gorman. “It is a whole-body experience and rewards those who take the time to linger.”