New York Times reporter Pam Belluck writes that MIT researchers have found exposure to a specific combination of light and sound could improve Alzheimer’s symptoms. “It’s stunning that the intervention had beneficial effects on so many different aspects of Alzheimer-like pathology,” said Dr. Lennart Mucke, director of the Gladstone Institute of Neurological Disease.
Dr. Francis Collins, director of the NIH, details how MIT researchers have developed a new low-energy imaging approach called three-photon microscopy that allows exploration of all six layers of the visual cortex in a mammal’s brain. Collins notes that the researchers are proving themselves to be “biological explorers of the first order.”
Prof. Earl Miller speaks with BuzzFeed reporter Terri Pous about the problems posed by multitasking. When it comes to juggling two tasks like driving and talking on the phone, Miller notes that "when someone is on the phone with you, they have no idea what’s going on in front of you. That’s just plain dangerous for drivers and anyone around them."
Local biotech companies raised money to help MIT’s Bear Lab study Fragile X syndrome by competing in lawn games, writes Allison Hagan for The Boston Globe. The $30,000 raised provides “a very real chance at a success in this disease, and it’s going to have a much broader impact,” says Prof. Mark Bear.
Boston Globe reporter Jonathan Saltzman spotlights postdoctoral associates Matheus Victor, Jarrett Smith and Quinton Smith. They have been selected by the Howard Hughes Medical Institute as Hanna Gray Fellows, a program that aims to encourage emerging young scientists who are underrepresented in life sciences.
Molly Webster of WNYC’s Radiolab visits the Picower Institute to learn more about how researchers are investigating new techniques that might eventually be used to treat Alzheimer’s disease. Prof. Li-Huei Tsai speaks about her group’s work using flickering light to reduce the beta amyloid plaque found in Alzheimer’s patients, and graduate student Dheeraj Roy discusses his work recovering memories with light.
In an article published by Wired, Jordana Cepelewicz highlights a study co-authored by Prof. Earl Miller that examines the capacity limit for the human brain’s working memory. Cepelewicz explains that the research, “not only provides insights into memory function and dysfunction, but also offers further evidence for a burgeoning theory of how the brain processes information.”
A new study led by Prof. Li-Huei Tsai reveals more information about the possible link between Alzheimer’s disease and the gene variant APOE4, writes Martin Finucane for The Boston Globe. The researchers discovered that by editing the gene into the more common APOE3 variant, “they could eliminate the signs of Alzheimer’s in brain cells,” said Finucane.
MIT researchers have identified the brain circuit required for observational learning, reports Xinhua. According to the study, the area involved in evaluating social information is more active when witnessing an experience and “relays information about the experience” to the region important for processing emotions.
Research by Prof. Susumu Tonegawa suggests that a specific region of the hippocampus plays a role in how memories can trigger a physical stress response, writes Fiona McMillan for Forbes. The findings, McMillan notes, are “providing new insight into the complex interplay between emotion, stress and memory.”
Prof. Li-Huei Tsai found that use of a small flickering light could prevent plaque-forming proteins in the brains of mice - a practice that has potential to combat Alzheimer’s disease. “The work offers the possibility of forestalling or even reversing the damage caused by such conditions without using a drug,” writes Helen Thomson for Nature.
Boston Magazine reporter Jamie Ducharme spotlights Prof. Li-Huei Tsai’s quest to vanquish Alzheimer’s disease. Ducharme writes that Tsai’s work, including two recent papers outlining potential treatments for Alzheimer’s, “established her as a bona fide rock star in the neuroscience world.”
A new study by MIT researchers shows that different types of learning correspond with different brainwave frequencies, reports Brooks Hays for UPI. The findings, “could help doctors diagnose and treat learning disabilities and cognitive diseases.”
Damien Garde of STAT highlights Prof. Li-Huei Tsai’s research on the HDAC2 enzyme in an article about Alzheimer’s research. “If we can reduce HDAC2 expression in Alzheimer’s disease models, we can reactivate the genes [that] actually rescue learning and memory,” says Prof. Tsai.
MIT scientists have discovered that memory creation and memory recall are not connected to the same detour circuit in the brain, reports Alyssa Meyers of the Boston Globe. With this new information, the researchers plan to study how “the circuit functions in the brains of patients with early stages of Alzheimer’s,” explains Meyers.