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New York Times reporter Pam Belluck writes that MIT researchers have found exposure to a specific combination of light and sound could improve Alzheimer’s symptoms. “It’s stunning that the intervention had beneficial effects on so many different aspects of Alzheimer-like pathology,” said Dr. Lennart Mucke, director of the Gladstone Institute of Neurological Disease.
Dr. Francis Collins, director of the NIH, details how MIT researchers have developed a new low-energy imaging approach called three-photon microscopy that allows exploration of all six layers of the visual cortex in a mammal’s brain. Collins notes that the researchers are proving themselves to be “biological explorers of the first order.”
Molly Webster of WNYC’s Radiolab visits the Picower Institute to learn more about how researchers are investigating new techniques that might eventually be used to treat Alzheimer’s disease. Prof. Li-Huei Tsai speaks about her group’s work using flickering light to reduce the beta amyloid plaque found in Alzheimer’s patients, and graduate student Dheeraj Roy discusses his work recovering memories with light.
In an article published by Wired, Jordana Cepelewicz highlights a study co-authored by Prof. Earl Miller that examines the capacity limit for the human brain’s working memory. Cepelewicz explains that the research, “not only provides insights into memory function and dysfunction, but also offers further evidence for a burgeoning theory of how the brain processes information.”
MIT scientists have discovered that memory creation and memory recall are not connected to the same detour circuit in the brain, reports Alyssa Meyers of the Boston Globe. With this new information, the researchers plan to study how “the circuit functions in the brains of patients with early stages of Alzheimer’s,” explains Meyers.
CBS Boston highlights a new study by MIT researchers that shows that blocking the HDAC2 enzyme could one day help restore memories in Alzheimer’s patients. Postdoctoral fellow Jay Penney explains that, “What we’ve done is found a new way to basically prevent this negative effect of this enzyme.”
Boston Magazine reporter Jamie Ducharme writes that MIT researchers have found that blocking the HDAC2 enzyme may potentially reverse memory loss in Alzheimer’s patients. The researchers, “blocked HDAC2 activity by preventing it from binding with Sp3, a protein coding gene that the team found to be a crucial part of genetic blockade formation.”
A study by MIT researcher suggests that the brain simultaneously creates long and short-term memories, reports Tim De Chant for NOVA. The findings suggest that one version “is filed away in the hippocampus, the center of short-term memories, while the other is stored in cortex, where our long-term memories reside.”
BBC News reporter James Gallagher writes that MIT researchers have found that the brain may simultaneously create short-term and long-term versions of memories. Prof. Susumu Tonegawa explains that “understanding how this happens may be relevant in brain disease patients.”
A new study by MIT researchers suggests that, contrary to previous findings, the human brain may store short-term and long-term memories at the same time, reports Andy Rosen for The Boston Globe. Rosen writes that the findings could “lead toward a better understanding of memory diseases like Alzheimer’s.”
The Boston Globe Magazine’s list of some of the most innovative ideas, people, and companies of 2016 features graduate student Dheeraj Roy, whose research suggests that one day optogenetics could potentially be used to help stimulate memories in patients with Alzheimer’s disease.
MIT researchers have found that flashing lights could potentially be used to stave off Alzheimer’s disease, writes Oscar Williams for The Huffington Post. “Light stimulation directed to the hippocampus, the part of the brain that processes memories, led to a reduction of…beta amyloid,” which is found in Alzheimer’s disease.
Financial Times reporter Clive Cookson writes that MIT researchers have found evidence that flashing lights could potentially be used as a noninvasive treatment for Alzheimer’s disease. The researchers found that “lights flashing on and off 40 times per second restored ‘gamma oscillation’ waves that were suppressed in the disease.”
MIT researchers have found that flashing light may reduce the buildup of beta amyloid protein in the brain, which is associated with Alzheimer’s disease, writes Michelle Roberts for the BBC News. The researchers hope that “clearing beta amyloid and stopping more plaques from forming could halt Alzheimer's and its symptoms.”
Writing for The Atlantic, Ed Yong spotlights a study by MIT researchers that identifies a potential new treatment for Alzheimer’s – using pulses of light to stimulate brain waves. Yong writes that the study “heralds a completely new approach to dealing with Alzheimer’s—changing neural activity, rather than delivering drugs or chemicals.”