• At left, photoreceptor cells of the retina have undergone severe damage after treatment with an alkylating agent. This damage is exacerbated by the DNA repair enzyme Aag. At right, photoreceptor cells lacking Aag appear normal following treatment with the alkylating agent.

    Why too much DNA repair can injure tissue

    Overactive repair system promotes cell death following DNA damage by certain toxins, study shows.

    MIT News