Capturing the complete process of embryonic development
By tracking over 1 million cells, researchers created a detailed map of embryonic development in mice. It could provide development and disease insights.
AI model decodes the language cells use to communicate
A new computational approach reveals how cells communicate to assemble into tissues. This could accelerate stem cell engineering, improve disease models, and inform therapies.
Advancing stem cell research and building the next generation of biologists
Biology PhD student Giselle Valdes studies stem cell regeneration while encouraging aspiring students and researchers.
Improving cartilage repair through cell therapy
SMART breakthrough offers a promising pathway toward improved manufacturing of high‑quality cells for regenerative therapies to treat joint diseases.
MIT researchers invent new human brain model to enable disease research, drug discovery
Cultured from induced pluripotent stem cells, “miBrains” integrate all major brain cell types and model brain structures, cellular interactions, activity, and pathological features.
MIT engineers turn skin cells directly into neurons for cell therapy
A new, highly efficient process for performing this conversion could make it easier to develop therapies for spinal cord injuries or diseases like ALS.
Knitted microtissue can accelerate healing
Lincoln Laboratory and MIT researchers are creating new types of bioabsorbable fabrics that mimic the unique way soft tissues stretch while nurturing growing cells.
A new wave of treatment for Alzheimer’s disease
Professor Li-Huei Tsai studies how brain waves can be used to treat neurodegenerative diseases such as Alzheimer’s.
Exploring the links between diet and cancer
Omer Yilmaz’s work on how diet influences intestinal stem cells could lead to new ways to treat or prevent gastrointestinal cancers.
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state
Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells; study establishes senescence as a potentially targetable mechanism for future treatment.
“SCOUT” helps researchers find, quantify significant differences among organoids
Unbiased, high-throughput analysis pipeline improves utility of “minibrains” for understanding development and diseases such as Zika infection.
Study finds path for addressing Alzheimer’s blood-brain barrier impairment
MIT researchers pinpoint mechanism and demonstrate that drugs could help.
Study links certain metabolites to stem cell function in the intestine
Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue.
Helping blood cells regenerate after radiation therapy
Method boosts differentiation of stem cells into mature blood cell types, may help leukemia and lymphoma patients.
In pursuit of the elusive stem cell
New MIT initiative delves into the biology of stem cells and cancer stem cells, seeks ways to identify, purify, and propagate them.